This data package consists of data from parallel experiments compared to Pck001 but performed with EndoC-βH1 cells instead of human islets. Cells were treated with IFNγ + IL-1β for 48 h and submitted to RNA-seq (n=5), ATAC-seq (n=5), DNA methylation (n=5), and H3K27Ac ChIP-seq (n=4). In addition...

This data package consists data from EndoC-βH1 (n=6) treated with IFNα for 8 and 24 h and submitted to RNA-seq analysis ( Table 1 ). This was generated in parallel with Pck008. Data contributors: Arturo Roca-Rivada, Xiaoyan Yi & Décio L. Eizirik: ULB Center for Diabetes Research, Medical Faculty...

This data package consists of data from MIN6 cells (n=4) treated with IL-1β + IFNγ + TNFα for 24 h post RNAi targeting 85/88 kDa calcium-independent phospholipase A2 ( Pla2g6 ) and submitted to proteomics analysis ( Table 1 ). Pla2g6 is an enzyme that metabolizes phosphatidylcholine (PCs) into...

This data package consists of data from paired human islets treated with IFNγ + IL-1β for 48 h and submitted to RNA-seq (n=5), ATAC-seq (n=5), UMI-4C18 (n=2 or 3, depending on the viewpoint), and ChIP-seq for histone H3 lysine 27 acetylation (H3K27Ac) (n=4) ( Table 1 ). Islets across the study...

This data package consists of data from human islets (n=5) treated with IFNγ + IL-1β for 48 h and submitted to RNA-seq analysis ( Table 1 ). Data contributors: Arturo Roca-Rivada, Xiaoyan Yi & Décio L. Eizirik: ULB Center for Diabetes Research, Medical Faculty, Université Libre de Bruxelles...

This data package consists of data from MIN6 cells treated with IL-1β + IFNγ + TNFα + palmitate for 24 h and submitted to proteomics analysis, and the same treatment for 8 h for metabolomics analysis (n=4) ( Table 1 ). This experimental design was set to study the possible roles of free fatty acids...

This data package consists of RNA-seq data from human islets (n=10) treated with IFNγ + IL-1β for 24 h ( Table 1 ). Data contributors: Wenting Wu & Carmella Evans-Molina: Center for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis, IN, USA. Farooq Syed: Center for...

This data package contains processed LC-MS proteomics results and analysis scripts associated with the paper "Assessing Degenerate Peptide Resolution Methods using a Ground Truth Dataset". In this study, we designed an artificial microbial community to create a ground truth, simulated metaproteomic...

Friction Stir Welding Processing Friction Stir Welding (FSW) is a solid-phase joining process achieved by spinning a tool and plunging it into the weld site. Frictional heating and material deformation enable the formation of a plasticized region below the tool shoulder called the stir-zone. The FSW...

Please cite as : Authors. Year. PNNL MCPC Characterization Round 1. [Data Set] PNNL DataHub. DOI This data is published under a CC0 license . The authors encourage data reuse and request attribution by referencing the above citations for the data package. Principal Researcher: Dr. Erin Barker...

Please cite as : Authors. Year. PNNL MCPC Characterization Round 2. [Data Set] PNNL DataHub. DOI This data is published under a CC0 license . The authors encourage data reuse and request attribution by referencing the above citations for the data package. Principal Researcher: Dr. Erin Barker...

Please cite as : Authors. Year. PNNL MCPC Characterization Round 3. [Data Set] PNNL DataHub. DOI This data is published under a CC0 license . The authors encourage data reuse and request attribution by referencing the above citations for the data package. Principal Researcher: Dr. Erin Barker...

Dataset Description The goal of the experiment was to demonstrate that the optimized multiplexed multi-PTM profiling workflow can comprehensively and quantitatively capture dynamic changes in protein abundance, cysteine oxidation, phosphorylation, and acetylation in cytokine-induced inflammatory...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson MERS-CoV Experiment MCL005 Metadata The purpose of this experiment was to evaluate the human host epigenetic response to MERS-CoV virus infection. Samples were obtained from human lung adenocarcinoma cells (Calu-3) and processed for...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson MERS-CoV Experiment MCL004 Metadata The purpose of this experiment was to evaluate the host response to MERS-CoV virus infection. Sample data was obtained from human lung adenocarcinoma cells (Calu-3) and processed for genome binding/occupancy...