Created on 2024-10-15T19:55:00+00:00 by LN Anderson ; Last updated 2024-11-13T15:01:44+00:00 and is pending public release before or by 2025-10-01. Human Liver Epithelium Response to HCoV-229E Infection Epigenomics (ACS-DP4) The purpose of this experiment was to evaluate how wild-type Human...
Created on 2024-10-15T19:55:00+00:00 by LN Anderson ; Last updated 2024-11-13T15:01:44+00:00 and is pending public release before or by 2025-10-01. Human Primary Airway Epithelium Response to HCoV-229E Infection Transcriptomics (ACS-DP3) The purpose of this experiment was to evaluate the human host...
Created 2024-09-17T19:19:38+00:00 by LN Anderson ; Last updated 2024-10-17T17:30:32+00:00 and is pending public release. Human A549 and MRC5 Cell Response to HCoV-229E Infection Transcriptomics (ACS-DP1) The purpose of this experiment was to evaluate the human host cellular response to wild-type...
MERS-CoV Experiment MDC001 Processed Omics Data Unavailable This experiment evaluated primary human dendritic cells infected with a wild type MERS-CoV (icMERS) virus. Related Experimental Data BioProject: PRJNA315103 GEO: GSE79172 (mRNA transcriptome response) Acknowledgment of Federal Funding The...
Coronaviruses (CoV) emerge suddenly from animal reservoirs to cause novel diseases in new hosts. Discovered in 2012, the Middle East respiratory syndrome coronavirus (MERS-CoV) is endemic in camels in the Middle East and is continually causing local outbreaks and epidemics. While all three newly...
The research goal of this project is to identify and control host functions hijacked during viral infection through use of PNNL ‘omics technologies and modeling capabilities.
Human infections caused by viral pathogens trigger a complex gamut of host responses that limit disease, resolve infection, generate immunity, and contribute to severe disease or death. Here, we present experimental methods and multi-omics data capture approaches representing the global host...
Last updated on 2025-02-03T23:25:06+00:00 by LN Anderson The Thermo Scientific™ Velos Pro™ Orbitrap Mass Spectrometer instrument data source combines advanced mass accuracy with an ultra-high resolution Orbitrap mass analyzer for increased sensitivity, enabling molecular weight determination for...
Last updated on 2025-02-03T23:25:06+00:00 by LN Anderson The Bruker Daltonics SolariX Magnetic Resonance Mass Spectrometry (MRMS) instruments are available for different magnetic field strengths of 7T, 12T and 15T. The SolariX XR and 2xR instruments use magnetron control technology and a newly...
The Thermo Scientific™ Q Exactive™ GC hybrid quadrupole Orbitrap Mass Spectrometer provides an unmatched combination of sensitivity, mass-accuracy and resolving power in a single analysis for the highest confidence in compound discovery, identification, and quantitation. With best-in-class...
Last updated on 2025-02-03T23:25:06+00:00 by LN Anderson The IONTOF TOF.SIMS 5 data source is a time-of-flight secondary ion mass spectrometer and powerful surface analysis tool used to investigate scientific questions in biological, environmental, and energy research. Among the most sensitive of...
Last updated on 2025-02-03T23:25:06+00:00 by LN Anderson The Thermo Scientific™ Q Exactive™ Plus Mass Spectrometer benchtop LC-MS/MS system combines quadruple precursor ion selection with high-resolution, accurate-mass (HRAM) Orbitrap detection to deliver exceptional performance and versatility...
Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson PNNL DataHub NIAID Program Project: Modeling Host Responses to Understand Severe Human Virus Infections, Multi-Omic Viral Dataset Catalog Collection Background The National Institute of Allergy and Infectious Diseases (NIAID) "Modeling Host...