This software aligns and generates a dataobject with sequencing and alignment metrics for use with short read nanopore sequencing data.

Background: New demands for water can be satisfied through a variety of source options. In some basins surface and/or groundwater may be available through permitting with the state water management agency (termed unappropriated water), alternatively water might be purchased and transferred out of...

Framework for Optimizing Reliable Energy Systems and Infrastructure Given High-uncertainty Trajectories (FORESIGHT) The FORESIGHT initiative develops a first-of-its-kind multi-system operational and near-term planning framework to systematically account for evolving probabilities of weather extremes...

Problem Statement and Objectives : Climate datasets are available across many institutions. Understanding which one to use, or how to combine the datasets, and for which application, or/and which region, and/or which specific fundamental science question is a challenge. A multi-lab PNNL-ANL...

Background In type 1 diabetes (T1D), autoimmune responses and inflammation cause the death of pancreatic β cells, leading to the body’s inability to produce insulin and maintain glucose homeostasis. This process is at least in part mediated by pro-inflammatory cytokines, such as interferon (IFN)α...

Biomineralization is the process by which organisms use biomolecules to produce hierarchically structured organic-inorganic composites. Using biology as inspiration, a protein construct (FD31) was previously designed to accelerate formation of nano-calcite with an unconventional {110} face. To...

Kate Hickcox joined Pacific Northwest National Laboratory (PNNL) in 2020 and focuses on advancing research in energy, buildings, industry, manufacturing, and communities, blending creative and practical approaches to uncover effective design solutions and strategies. Hickcox has worked in buildings...

Current methods for product or material input-output inventory data often require significant time and effort from manufacturers to compile. Additionally, without a uniform methodology these can result in inconsistent datasets that are difficult for practitioners to evaluate and compare, even within...

Dr. Donald Todd is an expert in nuclear reactor design and in executing novel nuclear safety analysis for nuclear plants. He is a co-editor with Dr. Alan E. Waltar of the book Fast Spectrum Reactors (2012), the 2016 Japanese translation of Fast Spectrum Reactors , and is an author of the “Boiling...

Kathy joined PNNL in September 2022, bringing with her a wealth of experience in the fields of Chemical Engineering and material science within the renewable energy sector. Her exposure to the extensive data science field during her chemical engineering endeavors inspired her transition into the...