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MERS-CoV Experiment MDC001 Processed Omics Data Unavailable This experiment evaluated primary human dendritic cells infected with a wild type MERS-CoV (icMERS) virus. Related Experimental Data BioProject: PRJNA315103 GEO: GSE79172 (mRNA transcriptome response) Acknowledgment of Federal Funding The...

The Human Islet Research Network (HIRN) is a large consortia with many research projects focused on understanding how beta cells are lost in type 1 diabetics (T1D) with a goal of finding how to protect against or replace the loss of functional beta cells. The consortia has multiple branches of...

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The Environmental Determinants of Diabetes in the Young (TEDDY) study is searching for factors influencing the development of type 1 diabetes (T1D) in children. Research has shown that there are certain genes that correlate to higher risk of developing T1D, but not all children with these genes...

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The Diabetes Autoimmunity Study in the Young (DAISY) seeks to find environmental factors that can trigger the development of type 1 diabetes (T1D) in children. DAISY follows children with high-risk of developing T1D based on family history or genetic markers. Genes, diets, infections, and...

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Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson PNNL DataHub NIAID Program Project: Modeling Host Responses to Understand Severe Human Virus Infections, Multi-Omic Viral Dataset Catalog Collection Background The National Institute of Allergy and Infectious Diseases (NIAID) "Modeling Host...

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Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Omics-LHV Profiling of Host Response to MERS-CoV Virus Infection Background Middle East Respiratory Syndrome coronavirus ( MERS-CoV ), part of the Coronaviridae family, is classified as a Category C priority pathogen by the National Institute...

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Machine learning is a core technology that is rapidly advancing within type 1 diabetes (T1D) research. Our Human Islet Research Network (HIRN) grant is studying early cellular response initiating β cell stress in T1D through the generation of heterogenous low- and high-throughput molecular...

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Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson MERS-CoV Experiment MMVE002 The purpose of this experiment was to evaluate the human host response to MERS-CoV (strain EMC-2012) infectious clone (icMERS-CoV) virus infection. Sample data was obtained from primary human microvascular...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson MERS-CoV Experiment MHAE001 The purpose of this experiment was to evaluate the human host response to wild-type MERS-CoV (icMERS-CoV) virus infection. Sample data was obtained from primary human airway epithelial (HAE) cells for mRNA, miRNA...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson MERS-CoV Experiment MHAE002 The purpose of this experiment was to evaluate the human host response to wild-type MERS-CoV (strain EMC-2012) virus infection. Sample data was obtained from primary human microvascular endothelial cells (HMVE) for...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson MERS-CoV Experiment MMVE001 The purpose of this experiment was to evaluate the human host response to MERS-CoV (strain EMC-2012) infectious clone (icMERS-CoV) virus infection. Sample data was obtained from primary human microvascular...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson MERS-CoV Experiment MMVE002 The purpose of this experiment was to evaluate the human host response to MERS-CoV (strain EMC-2012) infectious clone (icMERS-CoV) virus infection. Sample data was obtained from primary human fibroblast cells for...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson MERS-CoV Experiment MHAE003 The purpose of this experiment was to evaluate the human host response to wild-type MERS-CoV (strain EMC-2012) infection. Sample data was obtained from primary human airway epithelial cells (HAE) for mRNA...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson MERS-CoV Experiment MM001 The purpose of this experiment was to evaluate the host response to wild-type MERS-CoV virus infection. Sample data was obtained from primary mouse (strain C57BL/6J) whole lung for mRNA, proteomics, metabolomics, and...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson MERS-CoV Experiment MCL002 The purpose of this experiment was to evaluate the human host response to wild-type Middle Eastern Respiratory Syndrome coronavirus (MERS-CoV) and mutants icMERS-RFP, icMERS-DNSP16, and icMERS-d4B virus infection...