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Christine H Chang, William C Nelson, Abby Jerger, Aaron T Wright, Robert G Egbert, Jason E McDermott, Snekmer: a scalable pipeline for protein sequence fingerprinting based on amino acid recoding, Bioinformatics Advances , Volume 3, Issue 1, 2023, vbad005, https://doi.org/10.1093/bioadv/vbad005...

The rhizosphere represents a dynamic and complex interface between plant hosts and the microbial community found in the surrounding soil. While it is recognized that manipulating the rhizosphere has the potential to improve plant fitness and health, engineering the rhizosphere microbiome through...

Agriculture is the largest source of greenhouse gases (GHG) production. Conversion of nitrogen fertilizers into more reduced forms by microbes through a process known as biological nitrification drives GHG production, enhances proliferation of toxic algal blooms, and increases cost of crop...

Metabolite exchange between plant roots and their associated rhizosphere microbiomes underpins plant growth promotion by microbes. Sorghum bicolor is a cereal crop that feeds animals and humans and is used for bioethanol production. Its root tips exude large amounts of a lipophilic benzoquinone...

A major challenge in biotechnology and biomanufacturing is the identification of a set of biomarkers for perturbations and metabolites of interest. Here, we develop a data-driven, transcriptome-wide approach to rank perturbation-inducible genes from time-series RNA sequencing data for the discovery...

The Sequel II System Sequencer is a high-throughput DNA sequencer machine developed and manufactured by PacBio , and is designed for high throughput, production-scale sequencing laboratories. Originally released in 2015, the Sequel system provides Single Molecule, Real-Time (SMRT) sequencing core...

The Human Islet Research Network (HIRN) is a large consortia with many research projects focused on understanding how beta cells are lost in type 1 diabetics (T1D) with a goal of finding how to protect against or replace the loss of functional beta cells. The consortia has multiple branches of...

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"Moisture modulates soil reservoirs of active DNA and RNA viruses" Soil is known to harbor viruses, but the majority are uncharacterized and their responses to environmental changes are unknown. Here, we used a multi-omics approach (metagenomics, metatranscriptomics and metaproteomics) to detect...

Two factors that are well-known to influence soil microbiomes are the depth of the soil as well as the level of moisture. Previous works have demonstrated that climate change will increase the incidence of drought in soils, but it is unknown how fluctuations in moisture availability affect soil...

pmartR Software Overview The pmartR package provides a single software tool for QC (filtering and normalization), exploratory data analysis (EDA), and statistical analysis (robust to missing data) and includes numerous visualization capabilities of mass spectrometry (MS) omics data (proteomic...

Last updated on 2023-02-23T19:37:46+00:00 by LN Anderson Snekmer: A scalable pipeline for protein sequence fingerprinting using amino acid recoding (AAR) Snekmer is a software package designed to reduce the representation of protein sequences by combining amino acid reduction (AAR) with the kmer...

The long-term goals of this scientific focus area (SFA) are to develop flexible and extensible modeling capabilities that capture the dynamic multiscale interactions among climate, energy, water, land, socioeconomics, critical infrastructure, and other sectors and to use these capabilities to study...
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Some of the most rapid environmental changes on the planet are experienced in high-latitude regions. These changes affect all Earth system components, including the ocean, atmosphere, cryosphere, and marine and terrestrial ecosystems, and have both regional and global implications. The main...
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The influence of tidal inundation dynamics on below ground carbon pools is poorly understood across coastal terrestrial-aquatic interface (TAI) ecosystems. The dynamic environmental conditions of tidally-influenced landscapes, the chemically complex nature of carbon compounds, the diverse nature of...

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The Phenotypic Response of the Soil Microbiome to Environmental Perturbations Project (Soil Microbiome SFA) at Pacific Northwest National Laboratory is a Genomic Sciences Program Science Focus Area (SFA) Project operating under the Environmental Microbiome Science Research Area. The Soil Microbiome...

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