A major challenge in biotechnology and biomanufacturing is the identification of a set of biomarkers for perturbations and metabolites of interest. Here, we develop a data-driven, transcriptome-wide approach to rank perturbation-inducible genes from time-series RNA sequencing data for the discovery...
"Moisture modulates soil reservoirs of active DNA and RNA viruses" Soil is known to harbor viruses, but the majority are uncharacterized and their responses to environmental changes are unknown. Here, we used a multi-omics approach (metagenomics, metatranscriptomics and metaproteomics) to detect...
Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson PNNL DataHub NIAID Program Project: Modeling Host Responses to Understand Severe Human Virus Infections, Multi-Omic Viral Dataset Catalog Collection Background The National Institute of Allergy and Infectious Diseases (NIAID) "Modeling Host...
Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Omics-LHV Profiling of Host Response to West Nile Virus Infection Background West Nile virus ( WNV ) belongs to the mosquito-borne Flaviviridae family and is classified as a Category A priority pathogen by the National Institute of Allergy and...
Last updated on 2023-02-23T19:37:46+00:00 by LN Anderson PerCon SFA Project Publication Experimental Data Catalog The Persistence Control of Engineered Functions in Complex Soil Microbiomes Project (PerCon SFA) at Pacific Northwest National Laboratory ( PNNL ) is a Genomic Sciences Program...
Dr. Joshua Elmore is a Chemical Engineer at Pacific Northwest National Laboratory. He received his Ph. D. from the University of Georgia in the Department of Molecular Biology and Biochemistry studying the mechanisms of CRISPR/Cas microbial immune systems in hyperthermophilic Archaea. He was a...
Elise Van Fossen is a Post-Doctorate Research Associate in the Biological Sciences Division. Her research focuses on developing synthetic and chemical biology techniques for microorganism engineering.
Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson West Nile Virus Experiment WCB001 The purpose of this experiment was to evaluate the host response to West Nile virus (strain WNV-NY99) wild-type clone 382 and mutant 382-E218A 2 nt virus infection. Sample data was obtained from mouse (strain...
Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson West Nile Virus Experiment WCT001 The purpose of this experiment was to evaluate the host responseto West Nile virus (WNV-NY99) wild-type (strain 382) and mutant 382-E218A 2 nt virus infection. Sample data was obtained from mouse (strain C57BL...
Systems Virology Lethal Human Virus, SARS-CoV Experiment SM003 New uploads pending The purpose of this SARS experiment was to obtain samples for transcriptome and proteome analysis in C57BlL/6 mice lung infected with dicSARS CoV, SARS MA15 wild type and SARS BatSRBD mutant virus. Overall Design...
Systems Virology Lethal Human Virus, SARS-CoV Experiment SM012 New uploads pending The purpose of this SARS experiment was to obtain samples for transcriptome and proteome analysis in C57Bl/6 mice infected with SARS MA15 or SARS deltaORF6 mutant viruses. Overall Design: Twenty-week-old C57BL/6 mice...