Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Omics-LHV Profiling of Host Interferon-Stimulated Response to Virus Infection Background The human host Interferon ( IFN ) alpha, beta, and gamma participate in the body's natural immune response to lethal virus infection and disease. The...

The objective of Terrestrial-Aquatic Interface (TAI) research in PREMIS is to understand the factors governing C and nutrient movement and transformation through the TAI, and their sensitivities to inundation and salinity within coastal watersheds.

Accurate characterization of the global downward shortwave (SW) and photosynthetically active radiation (PAR) is fundamental for Earth system modeling and global change research. Combined with a machine-learning method, we used the Earth Polychromatic Imaging Camera (EPIC) data onboard the Deep...

Neisseria gonorrhoeae is a Gram-negative diplococcus that is responsible for the sexually transmitted infection gonorrhea, a high morbidity disease in the United States and worldwide. Over the last several years N. gonorrhoeae strains resistant to antibiotics used to treat this infection have begun...

Clinical Proteomic Tumor Analysis Consortium (CPTAC) ovarian cancer proteogenomics project. Characterization of tumors using proteomics and phosphoproteomics to identify signatures of drug resistance and characterize pathways associated with tumor versus normal tissue.

Coastal landscapes are increasingly exposed to seawater due to sea level rise and extreme weather events. The biogeochemical responses of these vulnerable ecosystems are poorly understood, limiting our ability to predict how their role in global biogeochemical cycles will shift under future...

The VAST Challenge 2019 presents three mini-challenges and a grand challenge for you to apply your visual analytics research and technologies to help a city grapple with the aftermath of an earthquake that damages their nuclear power plant. These challenges are open to participation by individuals...

The long-term goals of this scientific focus area (SFA) are to develop flexible and extensible modeling capabilities that capture the dynamic multiscale interactions among climate, energy, water, land, socioeconomics, critical infrastructure, and other sectors and to use these capabilities to study...

Machine learning is a core technology that is rapidly advancing within type 1 diabetes (T1D) research. Our Human Islet Research Network (HIRN) grant is studying early cellular response initiating β cell stress in T1D through the generation of heterogenous low- and high-throughput molecular...

PNNL’s Vision Statement for Equity in the Power Grid Drawing from a wealth of interdisciplinary research in grid modernization, PNNL is spearheading an effort to advance equity and energy justice through the role of scientific research with the goal of building an advanced national power grid...

Predictive Phenomics is addressing the grand challenge of understanding and predicting phenotype by identifying the molecular basis of function and enable function-driven design and control of biological systems .

Dr. Jason McDermott, senior research scientist, has extensive research experience in molecular and structural virology and data resource design, data integration and prediction of biological networks, bridging experimental and computational biology. Currently, his research interests include data...

Janet Jansson is Chief Scientist for Biology in the Biological Sciences Division and a Laboratory Fellow at the Pacific Northwest National Laboratory (PNNL). Jansson has more than 30 years of experience in microbial ecology. Jansson earned an M.S.in Soil Microbiology at Colorado State University...

Hyun Song’s research is directed toward developing modeling and computational tools for the simulation of cellular metabolism and microbial community dynamics. His research interest in metabolic modeling includes 1) omics data-guided estimation of flux distribution in a genome-scale metabolic...

Aaron Wright leads the Chemical Biology & Exposure Sciences Group in the Biological Sciences Division at PNNL. His highly collaborative and diverse chemical biology research team is focused on gaining an improved functional and mechanistic understanding of biological processes including: (a)...