Omics-LHV, West Nile Experiment WCD003 The purpose of this West Nile experiment was to obtain samples for omics analysis in mouse dendritic cell response to wild-type West Nile virus (WNV). Overall Design: Mouse dendritic cells (2 x 10^5) were treated with wild-type WNV and collected in parallel...
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Omics-LHV, West Nile Experiment WCN004 The purpose of this West Nile experiment was to obtain samples for omics analysis in mouse cerebral cortex neurons in response to wild-type West Nile Virus (WNV; WNV-NY99 382) and mutant WNV-E218A (WNV-NY99 382) viral infection. Overall Design: Mouse cortical...
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Omics-LHV, West Nile Experiment WGCN004 The purpose of this West Nile experiment was to obtain samples for omics analysis in primary mouse granule neuron cells infected with wild type West Nile virus (WNV-NY99 clone 382, WNVWT) and mutant virus (WNVE218A). Overall Design: Granule cell neurons from...
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"Moisture modulates soil reservoirs of active DNA and RNA viruses" Soil is known to harbor viruses, but the majority are uncharacterized and their responses to environmental changes are unknown. Here, we used a multi-omics approach (metagenomics, metatranscriptomics and metaproteomics) to detect...
Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Omics-LHV Profiling of Host Response to Ebola Virus Infection Background Ebola virus ( EBOV ) is a high risk biological agent, belonging to the Flaviviridae family, and is classified as a Category A priority pathogen by the National Institute...
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Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Omics-LHV Profiling of Host Response to Influenza A Virus Infection Background Influenza A virus ( IAV ) is a high risk biological agent belonging to the Orthomyxoviridae family is classified as a Category C priority pathogen by the National...
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Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Omics-LHV Profiling of Host Response to MERS-CoV Virus Infection Background Middle East Respiratory Syndrome coronavirus ( MERS-CoV ), part of the Coronaviridae family, is classified as a Category C priority pathogen by the National Institute...
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Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson PNNL DataHub NIAID Program Project: Modeling Host Responses to Understand Severe Human Virus Infections, Multi-Omic Viral Dataset Catalog Collection Background The National Institute of Allergy and Infectious Diseases (NIAID) "Modeling Host...
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Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Omics-LHV Profiling of Host Response to West Nile Virus Infection Background West Nile virus ( WNV ) belongs to the mosquito-borne Flaviviridae family and is classified as a Category A priority pathogen by the National Institute of Allergy and...
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PerCon SFA, Co-Investigator Vivian Lin earned her PhD in organic chemistry from the University of California, Berkeley with Professor Chris Chang, developing fluorescent probes for imaging redox active small molecules. Afterward, she traveled to Switzerland for a postdoctoral fellowship in the...
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Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson MERS-CoV Experiment MM001 The purpose of this experiment was to evaluate the host response to wild-type MERS-CoV virus infection. Sample data was obtained from primary mouse (strain C57BL/6J) whole lung for mRNA, proteomics, metabolomics, and...
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Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Interferon Experiment IFNaHUH001 The purpose of this experiment was to evaluate the human host cellular response to treatment with and without interferon alpha/beta (IFNα/β) treatment. Sample time course data was obtained from human hepatoma...
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Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Ebola Virus Experiment EHUH001 The purpose of this experiment was to evaluate the human host response to wild-type Zaire Ebola virus (strain Mayinga) and mutant virus infection. Samples were obtained from human hepatoma carcinoma cells (HUH-7)...