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A major challenge in biotechnology and biomanufacturing is the identification of a set of biomarkers for perturbations and metabolites of interest. Here, we develop a data-driven, transcriptome-wide approach to rank perturbation-inducible genes from time-series RNA sequencing data for the discovery...

HDF5 file containing 10,000 hydraulic transmissivity inputs and the corresponding hydraulic pressure field outputs for a two-dimensional saturated flow model of the Hanford Site. The inputs are generated by sampling a 1,000-dimensional Kosambi-Karhunen-Loève (KKL) model of the transmissivity field...

Human infections caused by viral pathogens trigger a complex gamut of host responses that limit disease, resolve infection, generate immunity, and contribute to severe disease or death. Here, we present experimental methods and multi-omics data capture approaches representing the global host...

Fusarium sp. DS682 Proteogenomics Statistical Data Analysis of SFA dataset download: 10.25584/KSOmicsFspDS682/1766303 . GitHub Repository Source: https://github.com/lmbramer/Fusarium-sp.-DS-682-Proteogenomics MaxQuant Export Files (txt) Trelliscope Boxplots (jsonp) Fusarium Report (.Rmd, html)...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson PNNL DataHub NIAID Program Project: Modeling Host Responses to Understand Severe Human Virus Infections, Multi-Omic Viral Dataset Catalog Collection Background The National Institute of Allergy and Infectious Diseases (NIAID) "Modeling Host...

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The Environmental Determinants of Diabetes in the Young (TEDDY) study is searching for factors influencing the development of type 1 diabetes (T1D) in children. Research has shown that there are certain genes that correlate to higher risk of developing T1D, but not all children with these genes...

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The Diabetes Autoimmunity Study in the Young (DAISY) seeks to find environmental factors that can trigger the development of type 1 diabetes (T1D) in children. DAISY follows children with high-risk of developing T1D based on family history or genetic markers. Genes, diets, infections, and...

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Machine learning is a core technology that is rapidly advancing within type 1 diabetes (T1D) research. Our Human Islet Research Network (HIRN) grant is studying early cellular response initiating β cell stress in T1D through the generation of heterogenous low- and high-throughput molecular...

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Last updated on 2023-04-24T18:38:03+00:00 by LN Anderson Instrument Data Source Profile Instrument Name: Agilent DNA Microarray Scanner Model: G25025C Data Type: Microarray hybridisation data (mRNA, miRNA) Method Taxon: Expression profiling by array, Non-coding RNA profiling by array Topic Areas...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Ebola Virus Experiment EHUH001 The purpose of this experiment was to evaluate the human host response to wild-type Zaire Ebola virus (strain Mayinga) and mutant virus infection. Samples were obtained from human hepatoma carcinoma cells (HUH-7)...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Ebola Virus Experiment EU937001 The purpose of this experiment was to evaluate the human host response to wild-type Zaire Ebola virus (strain Mayinga) and mutant virus infection. Samples were obtained from human histiocytic lymphoma cells...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Influenza A Virus Experiment IM101 The purpose of this experiment was to evaluate the host mouse response to Influenza A virus (subtype H5N1) wild-type strain Influenza A/Vietnam/1203/2004, Influenza A/Vietnam/1203/2004 mutant strains PB2-627E...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Ebola Virus Experiment EHUH003 The purpose of this experiment was to evaluate the human host response to wild-type Zaire Ebola virus (strain Mayinga) infection. Samples were obtained from human hepatoma carcinoma cells (HUH-7) infected with...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Ebola Virus Experiment EHUVEC001 The purpose of this experiment was to evaluate the human host response to wild-type Zaire Ebola virus (strain Mayinga) and mutant virus infection in VP30 expression background. Sample data was obtained from...

These GCAM v4.3 SSP-RCP-GCM Output Databases are made available under the Open Data Commons Attribution License: http://opendatacommons.org/licenses/by/1.0/ . GCAM v4.3 SSP-RCP-GCM plausible solution databases. Supplemental dataset to: Graham N.T., M.I. Hejazi, M. Chen, E. Davies, J.A. Edmonds, S.H...