Human infections caused by viral pathogens trigger a complex gamut of host responses that limit disease, resolve infection, generate immunity, and contribute to severe disease or death. Here, we present experimental methods and multi-omics data capture approaches representing the global host...
Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Omics-LHV Profiling of Host Response to MERS-CoV Virus Infection Background Middle East Respiratory Syndrome coronavirus ( MERS-CoV ), part of the Coronaviridae family, is classified as a Category C priority pathogen by the National Institute...
Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Omics-LHV Profiling of Host Response to Influenza A Virus Infection Background Influenza A virus ( IAV ) is a high risk biological agent belonging to the Orthomyxoviridae family is classified as a Category C priority pathogen by the National...
Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Omics-LHV Profiling of Host Response to West Nile Virus Infection Background West Nile virus ( WNV ) belongs to the mosquito-borne Flaviviridae family and is classified as a Category A priority pathogen by the National Institute of Allergy and...
Short Biography Caroline (Carrie) Harwood received her Ph.D. in microbiology from the University of Massachusetts and completed postdoctoral work at Yale University. She held academic appointments at Cornell University and the University of Iowa before moving to the University of Washington in 2005...
Last updated on 2023-04-24T18:38:03+00:00 by LN Anderson Instrument Data Source Profile Instrument Name: Agilent DNA Microarray Scanner Model: G25025C Data Type: Microarray hybridisation data (mRNA, miRNA) Method Taxon: Expression profiling by array, Non-coding RNA profiling by array Topic Areas...
Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Ebola Virus Experiment EHUH001 The purpose of this experiment was to evaluate the human host response to wild-type Zaire Ebola virus (strain Mayinga) and mutant virus infection. Samples were obtained from human hepatoma carcinoma cells (HUH-7)...
Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson MERS-CoV Experiment MM001 The purpose of this experiment was to evaluate the host response to wild-type MERS-CoV virus infection. Sample data was obtained from primary mouse (strain C57BL/6J) whole lung for mRNA, proteomics, metabolomics, and...
Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Ebola Virus Experiment EHUH003 The purpose of this experiment was to evaluate the human host response to wild-type Zaire Ebola virus (strain Mayinga) infection. Samples were obtained from human hepatoma carcinoma cells (HUH-7) infected with...
Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Influenza A Virus Experiment IM102 The purpose of this experiment was to evaluate the mouse host response to Influenza A virus (subtype H7N9) wild-type strain Influenza A/Anhui/1/2013 (AH1-WT) virus and mutants NS1-103F/106M (AH1-F/M) and...
Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Influenza A Virus Experiment IM103 The purpose of this experiment was to evaluate the host response to Influenza A virus (subtype H5N1) wild-type strain Influenza A/Vietnam/1203/2004 (VN1203) virus, mutant VN1203-NS1trunc124, and mock...
Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson West Nile Virus Experiment WCB001 The purpose of this experiment was to evaluate the host response to West Nile virus (strain WNV-NY99) wild-type clone 382 and mutant 382-E218A 2 nt virus infection. Sample data was obtained from mouse (strain...
Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Ebola Virus Experiment EU937001 The purpose of this experiment was to evaluate the human host response to wild-type Zaire Ebola virus (strain Mayinga) and mutant virus infection. Samples were obtained from human histiocytic lymphoma cells...
Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson West Nile Virus Experiment WCT001 The purpose of this experiment was to evaluate the host responseto West Nile virus (WNV-NY99) wild-type (strain 382) and mutant 382-E218A 2 nt virus infection. Sample data was obtained from mouse (strain C57BL...
Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Influenza A Virus Experiment IM101 The purpose of this experiment was to evaluate the host mouse response to Influenza A virus (subtype H5N1) wild-type strain Influenza A/Vietnam/1203/2004, Influenza A/Vietnam/1203/2004 mutant strains PB2-627E...