This data package consists of data from β-TC-6 cells treated with IFNγ + IL-1β for 4, 8 or 24 h (n=4) and submitted to enrichment of cysteine-containing peptides (redox), phosphopeptides and acetylated peptides. This enabled the analysis of proteomics, redox cysteine, phosphoproteomics and...
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This data package consists of data from human islets (n=5) treated with IFNγ + IL-1β for 48 h and submitted to RNA-seq analysis ( Table 1 ). Data contributors: Arturo Roca-Rivada, Xiaoyan Yi & Décio L. Eizirik: ULB Center for Diabetes Research, Medical Faculty, Université Libre de Bruxelles...
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This data package consists of data from human islets treated for 48 h with cytokines (IFNγ, TNFα, and/or IL1β), thapsigargin (TG), brefeldin A (BFA), or DMSO for the control (CTRL) and submitted for single-cell RNA-seq (n=5) and single-nucleus multi-omics sequencing (snMultiomics-seq, n=1) ( Table 1...
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This data package consists of data from human islets (n=6) treated with IFNγ + IL-1β for 24 h and subjected to top-down proteomics ( Table 1 ). Data contributors: Ashley N. Ives, Wei-Jun Qian & James M. Fulcher: Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA, 99354...
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This data package consists of data from human islets and EndoC-βH1 cells treated with IFNα for 2, 8, or 24 h and submitted to RNA-seq (human islets: n=6 & EndoC-βH1: n=5) and ATAC-seq (n=4). In parallel, a batch of cells (n=4) had proteomics, lipidomics, and metabolomics performed in the same...
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This data package consists of data from MIN6 cells (n=4) treated with IL-1β + IFNγ + TNFα for 24 h post-RNAi targeting ADP-ribosylhydrolase ARH3 (Adprhl2), and submitted to proteomics analysis ( Table 1 ). ARH3 is a hydrolase that keeps cellular ADP-ribosylation levels in check and is regulated by...
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This data package consists of data from human islets (n=5) treated with IFNγ + IL-1β with or without difluoromethylornithine (DFMO) and submitted to RNA-seq and proteomics analysis ( Table 1 ). DFMO is an inhibitor of ornithine decarboxylase (ODC), an enzyme of the polyamine pathway. Therefore, this...
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This data package contains processed LC-MS proteomics results and analysis scripts associated with the paper "Assessing Degenerate Peptide Resolution Methods using a Ground Truth Dataset". In this study, we designed an artificial microbial community to create a ground truth, simulated metaproteomic...
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Dataset Description The goal of the experiment was to demonstrate that the optimized multiplexed multi-PTM profiling workflow can comprehensively and quantitatively capture dynamic changes in protein abundance, cysteine oxidation, phosphorylation, and acetylation in cytokine-induced inflammatory...
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Currently pending public release.
Currently pending public release.
Dataset Description The purpose of this experiment was to evaluate the human host cellular response to wild type human coronavirus strain 229E (HCoV-229E) infection. Sample data was obtained for mock-infected and immortalized human lung fibroblasts (MRC-5) (MOI 5). Whole cell lysates were collected...
Created on 2024-10-16T17:27:40+00:00 by LN Anderson ; Last updated 2025-08-01T15:13:46+00:00. S. elongatus PCC 7942 LiP and TPP Structural Proteomics (JM-PB-DP3) The purpose of this experiment was to investigate structural alterations in proteins involved in central carbon metabolism and...
Dataset Description The purpose of this experiment was to evaluate the human host cellular response to wild-type Human coronavirus strain 229E (HCoV-229E) infection. Sample data was obtained for mock and infected immortalized human lung epithelial cells (A549) (MOI 5) nuclear extracts, immortalized...
This data is supplementary to the manuscript Expanding the access of wearable silicone wristbands in community-engaged research through best practices in data analysis and integration by Lisa M. Bramer, Holly M. Dixon, David J. Degnan, Diana Rohlman, Julie B. Herbstman, Kim A. Anderson, and Katrina...