Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson MERS-CoV Experiment MCL001 The purpose of this experiment was to evaluate the human host response to wild-type Middle Eastern Respiratory Syndrome coronavirus (MERS-CoV), and mutants icMERS-CoV-RFP, icMERS-CoV-dNSP16, icMERS-CoV-d4B, and...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Interferon Experiment IFNaHUH001 The purpose of this experiment was to evaluate the human host cellular response to treatment with and without interferon alpha/beta (IFNα/β) treatment. Sample time course data was obtained from human hepatoma...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Interferon Experiment IFNMVE001 The purpose of this experiment was to evaluate the human host interferon-stimulated cellular response to interferon alpha/beta (IFNαβ) or gamma (INFγ) treatment. Sample data was obtained from primary lung...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Interferon Experiment IFNFB001 The purpose of this experiment was to evaluate the human host cellular response to interferon alpha/beta (IFNα/β) or interferon gamma (IFNγ) treatment. Sample data was obtained from primary human lung fibroblast...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Interferon Experiment IFNaIHH001 The purpose of this experiment was to evaluate the host interferon-stimulated cellular response to interferon alpha (IFNα) treatment. Sample data was obtained from human immortalized human hepatocyte cells (IHH...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Interferon Experiment IFNaCL001 The purpose of this experiment was to evaluate the host interferon-stimulated cellular response to interferon alpha (IFNα) treatment. Sample data was obtained from human lung adenocarcinoma cells (Calu-3)...

This dataset contains time series data collected from devices and sensors in the PNNL Systems Engineering Building collected using the VOLTTRON platform. The data includes readings from HVAC, power, and lighting systems and was collected between March and July of 2018. This work was funded by the...

Background: New demands for water can be satisfied through a variety of source options. In some basins surface and/or groundwater may be available through permitting with the state water management agency (termed unappropriated water), alternatively water might be purchased and transferred out of...

Framework for Optimizing Reliable Energy Systems and Infrastructure Given High-uncertainty Trajectories (FORESIGHT) The FORESIGHT initiative develops a first-of-its-kind multi-system operational and near-term planning framework to systematically account for evolving probabilities of weather extremes...

Problem Statement and Objectives : Climate datasets are available across many institutions. Understanding which one to use, or how to combine the datasets, and for which application, or/and which region, and/or which specific fundamental science question is a challenge. A multi-lab PNNL-ANL...

Background In type 1 diabetes (T1D), autoimmune response and inflammation cause the death of pancreatic β cells, leading to the body’s inability to produce insulin and maintain glucose homeostasis. This process is at least in part mediated by pro-inflammatory cytokines, such as interferon (IFN)α...

Current methods for product or material input-output inventory data often require significant time and effort from manufacturers to compile. Additionally, without a uniform methodology these can result in inconsistent datasets that are difficult for practitioners to evaluate and compare, even within...

Predictive Phenomics Initiative (PPI) Project Data Catalog Collection The Predictive Phenomics Initiative (PPI) is an internal LDRD investment at Pacific Northwest National Laboratory focused on unraveling the mysteries of molecular function in complex biological systems. Explore PPI research...

PNNL’s Vision Statement for Equity in the Power Grid Drawing from a wealth of interdisciplinary research in grid modernization, PNNL is spearheading an effort to advance equity and energy justice through the role of scientific research with the goal of building an advanced national power grid...

Biography Carrie Nicora is a senior research scientist (chemist III) at PNNL, specializing in high-throughput scientific research sample management using modular automation techniques for processing a wide range of biological specimens for proteomic, metabolomic, and lipidomic analysis. She is an...