The Phenotypic Response of the Soil Microbiome to Environmental Perturbations Project (Soil Microbiome SFA) at Pacific Northwest National Laboratory is a Genomic Sciences Program Science Focus Area (SFA) Project operating under the Environmental Microbiome Science Research Area. The Soil Microbiome...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Omics-LHV Profiling of Host Interferon-Stimulated Response to Virus Infection Background The human host Interferon ( IFN ) alpha, beta, and gamma participate in the body's natural immune response to lethal virus infection and disease. The...

Neisseria gonorrhoeae is a Gram-negative diplococcus that is responsible for the sexually transmitted infection gonorrhea, a high morbidity disease in the United States and worldwide. Over the last several years N. gonorrhoeae strains resistant to antibiotics used to treat this infection have begun...

Clinical Proteomic Tumor Analysis Consortium (CPTAC) ovarian cancer proteogenomics project. Characterization of tumors using proteomics and phosphoproteomics to identify signatures of drug resistance and characterize pathways associated with tumor versus normal tissue.

The PNNL-SERDP database was constructed by PNNL to generate the quantitative infrared spectra of gases associated with biomass burning; the reference data are to allow detection and quantification of such gases via infrared absorption spectroscopy. Candidates for the database were selected based on...

Last updated on 2023-02-23T19:37:46+00:00 by LN Anderson PerCon SFA Project Publication Experimental Data Catalog The Persistence Control of Engineered Functions in Complex Soil Microbiomes Project (PerCon SFA) at Pacific Northwest National Laboratory ( PNNL ) is a Genomic Sciences Program...

The Environmental Determinants of Diabetes in the Young (TEDDY) study is searching for factors influencing the development of type 1 diabetes (T1D) in children. Research has shown that there are certain genes that correlate to higher risk of developing T1D, but not all children with these genes...

The Diabetes Autoimmunity Study in the Young (DAISY) seeks to find environmental factors that can trigger the development of type 1 diabetes (T1D) in children. DAISY follows children with high-risk of developing T1D based on family history or genetic markers. Genes, diets, infections, and...

Machine learning is a core technology that is rapidly advancing within type 1 diabetes (T1D) research. Our Human Islet Research Network (HIRN) grant is studying early cellular response initiating β cell stress in T1D through the generation of heterogenous low- and high-throughput molecular...

Predictive Phenomics is addressing the grand challenge of understanding and predicting phenotype by identifying the molecular basis of function and enable function-driven design and control of biological systems .

Spruce and Peatlands Responses Under Changing Environments (SPRUCE) site is the 8.1-ha S1 bog, a Picea mariana [black spruce] – Sphagnum spp. ombrotrophic bog forest in northern Minnesota, 40 km north of Grand Rapids, in the USDA Forest Service Marcell Experimental Forest (MEF). Two field research...

The Biomedical Resilience & Readiness in Adverse Operating Environments (BRAVE) Project develop new capabilities to improve health and performance of first responders in adverse operating environments common to national defense. The BRAVE project analyze biological samples, collect physiological...

Michelle Davison is a microbiologist with a love of challenging, creative, and multidisciplinary projects. She is interested in the role phage play in environmental systems, as well as the myriad ways they can be harnessed as tools. She has experience isolating, developing and working with non-model...

Biography Dr. Mary Lipton is currently a Staff Scientist at the Pacific Northwest National Laboratory and Adjunct Professor at Washington State University-Tri-Cities in Richland and Adjunct Professor in the Institute for Biological Chemistry and Washington State University Pullman. She is nationally...

Publications: 2018 Khan NE, Y Maezato, RS McClure, CJ Brislawn, JM Mobberley, NG Isern, WB Chrisler, LM Markillie, BM Barney, HS Song, WC Nelson, and HC Bernstein. 2018. "Phenotypic responses to interspecies competition and commensalism in a naturally-derived microbial co-culture." Scientific...