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Viral communities detected from three large grassland soil metagenomes with historically different precipitation moisture regimes.
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"Visualizing the Hidden Half: Plant-Microbe Interactions in the Rhizosphere" Plant roots and the associated rhizosphere constitute a dynamic environment that fosters numerous intra- and interkingdom interactions, including metabolite exchange between plants and soil mediated by root exudates and the...
Human infections caused by viral pathogens trigger a complex gamut of host responses that limit disease, resolve infection, generate immunity, and contribute to severe disease or death. Here, we present experimental methods and multi-omics data capture approaches representing the global host...
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Biography Kristin Burnum-Johnson is a senior scientist and team lead of the Biomolecular Pathways team at PNNL. Burnum-Johnson earned her PhD in Biochemistry from Vanderbilt University with Professor Richard M. Caprioli and then completed a postdoctoral fellowship at PNNL with Dr. Richard D. Smith...
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Biography Young-Mo Kim is a senior bioanalytical chemist at PNNL. He received his PhD from Pohang University of Science and Technology in the School of Environmental Science and Engineering, studying analysis of metabolites during the bacterial and fungal degradation of xenobiotic substrates using...
Biography Ernesto Nakayasu is a senior research scientist focused on understanding molecular mechanisms of diseases. Nakayasu has been applying systems biology and mass spectrometry-based omics measurements to study how pathogens and metabolic alterations cause human diseases; the goal is to...
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Biography Carrie Nicora is a senior research scientist (chemist III) at PNNL, specializing in high-throughput scientific research sample management using modular automation techniques for processing a wide range of biological specimens for proteomic, metabolomic, and lipidomic analysis. She is an...
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Biography Dr. Smith's research interests span the development of advanced analytical methods and instrumentation, with particular emphasis on high-resolution separations and mass spectrometry, and their applications in biological and biomedical research. This has included creating and applying new...
Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson MERS-CoV Experiment MMVE002 The purpose of this experiment was to evaluate the human host response to MERS-CoV (strain EMC-2012) infectious clone (icMERS-CoV) virus infection. Sample data was obtained from primary human microvascular...
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Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Ebola Virus Experiment EHUH002 The purpose of this experiment was to evaluate the human host response to wild-type Zaire Ebola virus (strain Mayinga) and mutant virus infection. Samples were obtained from human hepatoma carcinoma cells (HUH-7)...
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Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Influenza A Virus Experiment ICL102 The purpose of this experiment was to evaluate the human host cellular response to Influenza A virus (subtype H7N9) , wild-type strain Influenza A/Anhui/1/2013 (AH1-WT), and mutant viruses NS1-L103F/I106M...
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Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson MERS-CoV Experiment MHAE001 The purpose of this experiment was to evaluate the human host response to wild-type MERS-CoV (icMERS-CoV) virus infection. Sample data was obtained from primary human airway epithelial (HAE) cells for mRNA, miRNA...
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Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson MERS-CoV Experiment MHAE002 The purpose of this experiment was to evaluate the human host response to wild-type MERS-CoV (strain EMC-2012) virus infection. Sample data was obtained from primary human microvascular endothelial cells (HMVE) for...
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Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson MERS-CoV Experiment MMVE001 The purpose of this experiment was to evaluate the human host response to MERS-CoV (strain EMC-2012) infectious clone (icMERS-CoV) virus infection. Sample data was obtained from primary human microvascular...