As part of the Pacific Northwest National Laboratory’s (PNNL) Science Focus Area program, we are investigating the impact of environmental change on microbial community function in grassland soils. Three grassland soils, representing different moisture regimes, were selected for ultra-deep...
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"DNA Viral Diversity, Abundance, and Functional Potential Vary across Grassland Soils with a Range of Historical Moisture Regimes" Soil viruses are abundant, but the influence of the environment and climate on soil viruses remains poorly understood. Here, we addressed this gap by comparing the...
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Publication
Human infections caused by viral pathogens trigger a complex gamut of host responses that limit disease, resolve infection, generate immunity, and contribute to severe disease or death. Here, we present experimental methods and multi-omics data capture approaches representing the global host...
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The Biomedical Resilience & Readiness in Adverse Operating Environments (BRAVE) Project develop new capabilities to improve health and performance of first responders in adverse operating environments common to national defense. The BRAVE project analyze biological samples, collect physiological...
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Last updated on 2024-03-03T02:26:52+00:00 by LN Anderson The Thermo Scientific™ Q Exactive™ Plus Mass Spectrometer benchtop LC-MS/MS system combines quadruple precursor ion selection with high-resolution, accurate-mass (HRAM) Orbitrap detection to deliver exceptional performance and versatility...
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Biography Ernesto Nakayasu is a senior research scientist focused on understanding molecular mechanisms of diseases. Nakayasu has been applying systems biology and mass spectrometry-based omics measurements to study how pathogens and metabolic alterations cause human diseases; the goal is to...
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Person
PerCon SFA, Co-Investigator Vivian Lin earned her PhD in organic chemistry from the University of California, Berkeley with Professor Chris Chang, developing fluorescent probes for imaging redox active small molecules. Afterward, she traveled to Switzerland for a postdoctoral fellowship in the...
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Data Source
Last updated on 2024-03-03T02:26:52+00:00 by LN Anderson The Thermo Scientific™ Velos Pro™ Orbitrap Mass Spectrometer instrument data source combines advanced mass accuracy with an ultra-high resolution Orbitrap mass analyzer for increased sensitivity, enabling molecular weight determination for...
Data Source
Bruker Daltonics SolariX Magnetic Resonance Mass Spectrometry (MRMS) instruments are available for different magnetic field strengths of 7T, 12T and 15T. The SolariX XR and 2xR instruments use magnetron control technology and a newly developed, high sensitivity, low noise preamplifier to exploit...
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The IONTOF TOF.SIMS 5 data source is a time-of-flight secondary ion mass spectrometer and powerful surface analysis tool used to investigate scientific questions in biological, environmental, and energy research. Among the most sensitive of surface analysis tools, it uses a high-vacuum technique...
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The Thermo Scientific™ Q Exactive™ GC hybrid quadrupole Orbitrap Mass Spectrometer provides an unmatched combination of sensitivity, mass-accuracy and resolving power in a single analysis for the highest confidence in compound discovery, identification, and quantitation. With best-in-class...
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Omics Lethal Human Virus, SARS-CoV Experiment SM001 New uploads pending The purpose of this experiment was to evaluate the human host response to Severe Acute Respiratory Syndrome coronavirus (SARS-CoV) wild-type virus. Sample data was obtained for 20 week-old C57BL/6J mouse lung tissue infected...
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Please cite as : Anderson L.N., W.C. Nelson, J.E. McDermott, R. Wu, S.J. Fansler, Y. Farris, and J.K. Jansson, et al. 2020. IA-TmG.1.0 (Metagenome, IA). [Data Set] PNNL DataHub. https://doi.org/10.25584/IATmG1/1635005 To enable a comprehensive survey of the metabolic potential of complex soil...
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Please cite as : Anderson L.N., W.C. Nelson, J.E. McDermott, R. Wu, S.J. Fansler, Y. Farris, and J.K. Jansson, et al. 2020. KS-TmG.1.0 (Metagenome, KS). [Data Set] PNNL DataHub. https://doi.org/10.25584/KSTmG1/1635004 To enable a comprehensive survey of the metabolic potential of complex soil...
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Please cite as : Anderson L.N., W.C. Nelson, J.E. McDermott, R. Wu, S.J. Fansler, Y. Farris, and J.K. Jansson, et al. 2020. WA-TmG.1.0 (Metagenome, WA). [Data Set] PNNL DataHub. https://doi.org/10.25584/WATmG1/1635002 To enable a comprehensive survey of the metabolic potential of complex soil...
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