This data package consists of data from human islets treated for 48 h with cytokines (IFNγ, TNFα, and/or IL1β), thapsigargin (TG), brefeldin A (BFA), or DMSO for the control (CTRL) and submitted for single-cell RNA-seq (n=5) and single-nucleus multi-omics sequencing (snMultiomics-seq, n=1) ( Table 1...

This data package consists of RNA-seq data from human islets (n=10) treated with IFNγ + IL-1β for 24 h ( Table 1 ). Data contributors: Wenting Wu & Carmella Evans-Molina: Center for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis, IN, USA. Farooq Syed: Center for...

This data package consists of data from parallel experiments compared to Pck001 but performed with EndoC-βH1 cells instead of human islets. Cells were treated with IFNγ + IL-1β for 48 h and submitted to RNA-seq (n=5), ATAC-seq (n=5), DNA methylation (n=5), and H3K27Ac ChIP-seq (n=4). In addition...

The data package consists of data from iPSC: HEL115.6-derived islet-like aggregates treated with IFNα for 24 h and submitted to RNA-seq (n=5) and scRNA-seq (n=5). ( Table 1 ). Data contributors: Arturo Roca-Rivada, Xiaoyan Yi & Décio L. Eizirik: ULB Center for Diabetes Research, Medical Faculty...

This data package consists data from EndoC-βH1 (n=6) treated with IFNα for 8 and 24 h and submitted to RNA-seq analysis ( Table 1 ). This was generated in parallel with Pck008. Data contributors: Arturo Roca-Rivada, Xiaoyan Yi & Décio L. Eizirik: ULB Center for Diabetes Research, Medical Faculty...

This data package consists of data from sets of β-TC-3 cells (n=3) treated with IL-1β + IFNγ + TNFα for 24 h with or without ML351 and submitted to RNA-seq ( Table 1 ). ML351 is an inhibitor of 12-lipoxygenase, an enzyme that produces 12-HETE. Therefore, this treatment was done to study whether...

This data package consists of data from MIN6 cells (n=4) treated with IL-1β + IFNγ + TNFα and RNAi targeting Poly(ADP)ribosyl polymerase 12 ( Parp12 ) for 24 h and submitted to proteomic analyses ( Table 1 ). PARP12 is an interferon-induced protein known to target viral RNA to stress granules. It...

Please cite as : Mary S. Lipton, William C. Nelson, Hugh McCullough, Montana L. Smith, Sheryl L. Bell, Lisa M. Bramer, Hyun-Seob Song, Kirsten Hofmockel, 2025. Moisture Metaphenome Incubation Analysis Results . [Data Set] PNNL DataHub. https://doi.org/10.25584/3007775 This data is published under a...

RhizoGrid Indexed Sorghum Rhizosphere Multi-Omics Identification of spatially resolved biomarkers of drought in Sorghum bicolor rhizosphere molecular-microbe interactions using a novel root cartography "RhizoGrid" system for sampling plants under drought and control conditions across 10 equally...

This data package contains processed LC-MS proteomics results and analysis scripts associated with the paper "Assessing Degenerate Peptide Resolution Methods using a Ground Truth Dataset". In this study, we designed an artificial microbial community to create a ground truth, simulated metaproteomic...

Please cite as : Josué A. Rodríguez-Ramos, Amy E. Zimmerman, Ruonan Wu, Sheryl Bell, Trinidad Alfaro, Kirsten Hofmockel, William C. Nelson. Soil DNA and RNA Virus Sequence Data Recovered Using Different Preparation Methods. https://doi.org/10.25584/2583337 This data is published under a CC0 license...

Please cite as : Robert E. Danczak, Sheryl Bell, Evan Warburton, Trinidad Alfaro, Kirsten Hofmockel, Amy E. Zimmerman, William C. Nelson, 2025. Bacterial/Fungal interaction multi-omics over a moisture gradient . [Data Set] PNNL DataHub. https://doi.org/10.25584/2574929 This data is published under a...

Dataset Description The goal of the experiment was to demonstrate that the optimized multiplexed multi-PTM profiling workflow can comprehensively and quantitatively capture dynamic changes in protein abundance, cysteine oxidation, phosphorylation, and acetylation in cytokine-induced inflammatory...

Data package for Lipids represent a dynamic, yet stable pool of microbially-derived soil carbon This data is published under a CC0 license . The authors encourage data reuse and request attribution by referencing the below citations for the data packages and associated manuscript. Please cite as...

Please cite as : McClure, R. and Janet Jansson. 2025. EVT 16s Data and Large Supplementary Files . [Data Set] PNNL DataHub. https://doi.org/10.25584/2530740. This data is published under a CC0 license . The authors encourage data reuse and request attribution by referencing the above citations for...