The data package consists of data from iPSC: HEL115.6-derived islet-like aggregates treated with IFNα for 24 h and submitted to RNA-seq (n=5) and scRNA-seq (n=5). ( Table S1 ). Data contributors: Arturo Roca-Rivada, Xiaoyan Yi & Décio L. Eizirik: ULB Center for Diabetes Research, Medical Faculty...

It consists of human islets (n=10, subdivided into 2 batches) treated with IFNγ + IL-1β for 24 h and submitted to proteomics, lipidomics and metabolomics in the same samples ( Table S1 ) Data contributors: Ernesto S. Nakayasu, Jennifer E. Kyle, Young-Mo Kim, Soumyadeep Sarkar & Thomas O. Metz...

This data package consists of data from MIN6 cells treated with IL-1β + IFNγ + TNFα + palmitate for 24 h and submitted to proteomics analysis, and the same treatment for 8 h for metabolomics analysis (n=4) ( Table S1 ). This experimental design was set to study the possible roles of free fatty acids...

This data package consists of data from β-TC-6 cells treated with IFNγ + IL-1β for 4, 8 or 24 h (n=4) and submitted to enrichment of cysteine-containing peptides (redox), phosphopeptides and acetylated peptides. This enabled the analysis of proteomics, redox cysteine, phosphoproteomics and...

The data package consists of RNA-seq datasets of EndoC-βH1 cells treated in parallel with IFNα, IFNγ, IL-1β and TNFα for 24 h and submitted to RNA-seq (n=4) ( Table S1 ) Data contributors: Arturo Roca-Rivada, Xiaoyan Yi & Décio L. Eizirik: ULB Center for Diabetes Research, Medical Faculty...

This data package consists of data from parallel experiments compared to Pck001 but performed with EndoC-βH1 cells instead of human islets. Cells were treated with IFNγ + IL-1β for 48 h and submitted to RNA-seq (n=5), ATAC-seq (n=5), DNA methylation (n=5), and H3K27Ac ChIP-seq (n=4). In addition...

This data package consists of data from MIN6 cells (n=4) treated with IL-1β + IFNγ + TNFα for 24 h post-RNAi targeting ADP-ribosylhydrolase ARH3 (Adprhl2), and submitted to proteomics analysis ( Table S1 ). ARH3 is a hydrolase that keeps cellular ADP-ribosylation levels in check and is regulated by...

This data package consists of mouse MIN6 cells treated with IL-1β + IFNγ + TNFα for 0 min, 15 min, 2 hr, and 24 hr, alongside an untreated 24 hr control, and submitted to global and PTM proteomics (carbamylation and acetylation) analysis (n=3) ( Table S1 ). This was designed to characterize the...

This data package consists of data from MIN6 cells (n=3) treated with IFNγ + IL-1β + TNFα with or without DFMO or N1,N11-diethylnorspermine (DENSpm) and submitted to RNA-seq ( Table S1 ). DENSpm is an inhibitor of ornithine decarboxylase (ODC) and polyamine oxidase (PAOX), both enzymes in the...

Please cite as : Mary S. Lipton, William C. Nelson, Hugh McCullough, Montana L. Smith, Sheryl L. Bell, Lisa M. Bramer, Hyun-Seob Song, Kirsten Hofmockel, 2025. Moisture Metaphenome Incubation Analysis Results . [Data Set] PNNL DataHub. https://doi.org/10.25584/3007775 This data is published under a...

RhizoGrid Indexed Sorghum Rhizosphere Multi-Omics Identification of spatially resolved biomarkers of drought in Sorghum bicolor rhizosphere molecular-microbe interactions using a novel root cartography "RhizoGrid" system for sampling plants under drought and control conditions across 10 equally...

This data package contains processed LC-MS proteomics results and analysis scripts associated with the paper "Assessment of Protein Inference Methods for Metaproteomics". In this study, we designed an artificial microbial community to create a simulated metaproteomic dataset which intentionally...

Please cite as : Josué A. Rodríguez-Ramos, Amy E. Zimmerman, Ruonan Wu, Sheryl Bell, Trinidad Alfaro, Kirsten Hofmockel, William C. Nelson. Soil DNA and RNA Virus Sequence Data Recovered Using Different Preparation Methods. https://doi.org/10.25584/2583337 This data is published under a CC0 license...

Please cite as : Robert E. Danczak, Sheryl Bell, Evan Warburton, Trinidad Alfaro, Kirsten Hofmockel, Amy E. Zimmerman, William C. Nelson, 2025. Bacterial/Fungal interaction multi-omics over a moisture gradient . [Data Set] PNNL DataHub. https://doi.org/10.25584/2574929 This data is published under a...

Dataset Description The goal of the experiment was to demonstrate that the optimized multiplexed multi-PTM profiling workflow can comprehensively and quantitatively capture dynamic changes in protein abundance, cysteine oxidation, phosphorylation, and acetylation in cytokine-induced inflammatory...