Biography Ernesto Nakayasu is a senior research scientist focused on understanding molecular mechanisms of diseases. Nakayasu has been applying systems biology and mass spectrometry-based omics measurements to study how pathogens and metabolic alterations cause human diseases; the goal is to...
The Thermo Scientific LTQ Orbitrap Velos combines the proven mass accuracy and ultra-high resolution of the Orbitrap mass analyzer, with the increased sensitivity and improved cycle time of the LTQ Velos. The high mass accuracy of the LTQ Orbitrap Velos increases the speed and condense of indication...
The IONTOF TOF.SIMS 5 data source is a time-of-flight secondary ion mass spectrometer and powerful surface analysis tool used to investigate scientific questions in biological, environmental, and energy research. Among the most sensitive of surface analysis tools, it uses a high-vacuum technique...
LIQUID Software Overview LIQUID provides users with the capability to process high throughput data and contains a customizable target library and scoring model per project needs. The graphical user interface provides visualization of multiple lines of spectral evidence for each lipid identification...
PerCon SFA Project Publication Linked Data Catalog (uploads pending) The Persistence Control of Engineered Functions in Complex Soil Microbiomes Project (PerCon SFA), at Pacific Northwest National Laboratory (PNNL) is a Genomic Sciences Program, Biosystems Design, Research Science Focus Area project...
"Visualizing the Hidden Half: Plant-Microbe Interactions in the Rhizosphere" Plant roots and the associated rhizosphere constitute a dynamic environment that fosters numerous intra- and interkingdom interactions, including metabolite exchange between plants and soil mediated by root exudates and the...
Multi-Omics Extended Data Package DOI Rapid Remodeling of the Soil Lipidome in Response to a Drying-Rewetting Event This study reveals specific changes in lipids and metabolites that are indicative of stress adaptation, substrate use, and cellular recovery during soil drying and subsequent rewetting...
MPLEx Method Protocol for Integrative Single-Sample Processing for Subsequent Proteomic, Metabolomic, and Lipidomic Analyses The Metabolite, Protein and Lipid Extraction (MPLEx) method protocol is a robust sample processing technique applicable to a breadth of diverse sample types, including various...
KS4A-Omics1.0_FspDS68 Fungal Monoisolate Multi-Omics Data Package DOI "A mineral doped micromodel platform demonstrates fungal bridging of carbon hotspots and hyphal transport of mineral derived nutrients" Molecular mechanisms underlying fungal mineral weathering and nutrient translocation in low...
Omics-LHV Profiling of Host Response to Influenza A Virus Infection Background: Influenza A viruses (IAV) are classified as a Category C priority pathogen, by the National Institute of Allergy and Infectious Diseases (NIAID), and are known to cause severe and even fatal infections in humans where...
Reusable Digital Data Lifecycle Downloads for Modeling Host Responses to Understand Severe Human Virus Infections The National Institute of Allergy and Infectious Diseases (NIAID) "Modeling Host Responses to Understand Severe Human Virus Infections" (U19AI106772) program project was a highly...
Influenza A Experiment IM104 Processed Omics Data Unavailable This Influenza experiment evaluated mouse lung expression after etoposide treatment and infection with a pandemic H1N1 influenza strain. Related Experimental Data BioProject: PRJNA382278 GEO: GSE97555 (mRNA transcriptome response)...
Ebola Experiment EIHH002 Processed Omics Data Unavailable This experiment evaluated Immortalized Human Hepatocyte (IHH) cell line host response to response to genetically-reconstructed Zaire Ebola virus infection. Related Experimental Data BioProject: PRJNA287217, PRJNA287216 GEO Accession: GSE69942...
Ebola Experiment EIHH001 Processed Omics Data Unavailable This experiment evaluated Immortalized Human Hepatocyte (IHH) cell line host response to wild-type Ebola viruses Zaire Ebola (ZEBOV '76) and Reston Ebola (REBOV '08) viral infection. Related Primary Data profiling by array BioProject...
MERS-CoV Experiment MDC001 Processed Omics Data Unavailable This experiment evaluated primary human dendritic cells infected with a wild type MERS-CoV (icMERS) virus. Related Experimental Data BioProject: PRJNA315103 GEO: GSE79172 (mRNA transcriptome response) Acknowledgment of Federal Funding The...