Comprised of 6,426 sample runs, The Environmental Determinants of Diabetes in the Young (TEDDY) proteomics validation study constitutes one of the largest targeted proteomics studies in the literature to date. Making quality control (QC) and donor sample data available to researchers aligns with...
Last updated on 2024-06-04T17:11:36+00:00 by LN Anderson PerCon SFA: Profiling sorghum-microbe interactions with a specialized photoaffinity probe identifies key sorgoleone binders in Acinetobacter pitti Mass spectrometry-based global proteome analysis and SoDA-PAL photoaffinity probe labeled...
Inclusion levels of alternative splicing (AS) events of five different varieties (i.e. skipped exon (SE), retained intron (RI), alternative 5’ splice site (A5SS), alternative 3’ splice site (A3SS), and mutually exclusive exons (MXE)) were measured in human blood samples from two separate cohorts of...
Rapid remodeling of the soil lipidome in response to a drying-rewetting event - Multi-Omics Data Package DOI Data package contents reported here are the first version and contain pre- and post-processed data acquisition and subsequent downstream analysis files using various data source instrument...
Please cite as : Anderson L.N., R. Wu, W.C. Nelson, J.E. McDermott, K.S. Hofmockel, and J.K. Jansson. 2021. WA-TmG.2.0 (Metagenome, WA). [Data Set] PNNL DataHub. https://doi.org/10.25584/WATmG2/1770324 Soil samples were collected in triplicate in the fall of 2017 across the three grassland...
Please cite as : Anderson L.N., R. Wu, W.C. Nelson, J.E. McDermott, K.S. Hofmockel, and J.K. Jansson. 2021. KS-TmG.2.0 (Metagenome, KS). [Data Set] PNNL DataHub. https://doi.org/10.25584/KSTmG2/1770332 Soil samples were collected in triplicate in the fall of 2017 across the three grassland locations...
Last updated on 2023-05-02T18:08:23+00:00 by LN Anderson Fungal Monoisolate Multi-Omics Data Package DOI "KS4A-Omics1.0_FspDS68" Molecular mechanisms underlying fungal mineral weathering and nutrient translocation in low nutrient environments remain poorly resolved, due to the lack of a platform for...
Biomedical Resilience & Readiness in Adverse Operating Environments (BRAVE) Project: Exhaled Breath Condensate (EBC) TMT Proteomic Transformation Data Exhaled breath condensate (EBC) represents a low-cost and non-invasive means of examining respiratory health. EBC has been used to discover and...
"Moisture modulates soil reservoirs of active DNA and RNA viruses" Soil is known to harbor viruses, but the majority are uncharacterized and their responses to environmental changes are unknown. Here, we used a multi-omics approach (metagenomics, metatranscriptomics and metaproteomics) to detect...
A major challenge in biotechnology and biomanufacturing is the identification of a set of biomarkers for perturbations and metabolites of interest. Here, we develop a data-driven, transcriptome-wide approach to rank perturbation-inducible genes from time-series RNA sequencing data for the discovery...
The Sequel II System Sequencer is a high-throughput DNA sequencer machine developed and manufactured by PacBio , and is designed for high throughput, production-scale sequencing laboratories. Originally released in 2015, the Sequel system provides Single Molecule, Real-Time (SMRT) sequencing core...
The Environmental Determinants of Diabetes in the Young (TEDDY) study is searching for factors influencing the development of type 1 diabetes (T1D) in children. Research has shown that there are certain genes that correlate to higher risk of developing T1D, but not all children with these genes...
The Diabetes Autoimmunity Study in the Young (DAISY) seeks to find environmental factors that can trigger the development of type 1 diabetes (T1D) in children. DAISY follows children with high-risk of developing T1D based on family history or genetic markers. Genes, diets, infections, and...
Machine learning is a core technology that is rapidly advancing within type 1 diabetes (T1D) research. Our Human Islet Research Network (HIRN) grant is studying early cellular response initiating β cell stress in T1D through the generation of heterogenous low- and high-throughput molecular...
pmartR Software Overview The pmartR package provides a single software tool for QC (filtering and normalization), exploratory data analysis (EDA), and statistical analysis (robust to missing data) and includes numerous visualization capabilities of mass spectrometry (MS) omics data (proteomic...
