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"DNA Viral Diversity, Abundance, and Functional Potential Vary across Grassland Soils with a Range of Historical Moisture Regimes" Soil viruses are abundant, but the influence of the environment and climate on soil viruses remains poorly understood. Here, we addressed this gap by comparing the...
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"Visualizing the Hidden Half: Plant-Microbe Interactions in the Rhizosphere" Plant roots and the associated rhizosphere constitute a dynamic environment that fosters numerous intra- and interkingdom interactions, including metabolite exchange between plants and soil mediated by root exudates and the...
Human infections caused by viral pathogens trigger a complex gamut of host responses that limit disease, resolve infection, generate immunity, and contribute to severe disease or death. Here, we present experimental methods and multi-omics data capture approaches representing the global host...
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"Moisture modulates soil reservoirs of active DNA and RNA viruses" Soil is known to harbor viruses, but the majority are uncharacterized and their responses to environmental changes are unknown. Here, we used a multi-omics approach (metagenomics, metatranscriptomics and metaproteomics) to detect...
Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson MERS-CoV Experiment MMVE002 The purpose of this experiment was to evaluate the human host response to MERS-CoV (strain EMC-2012) infectious clone (icMERS-CoV) virus infection. Sample data was obtained from primary human fibroblast cells for...
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Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson MERS-CoV Experiment MMVE002 The purpose of this experiment was to evaluate the human host response to MERS-CoV (strain EMC-2012) infectious clone (icMERS-CoV) virus infection. Sample data was obtained from primary human microvascular...
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Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Ebola Virus Experiment EHUH001 The purpose of this experiment was to evaluate the human host response to wild-type Zaire Ebola virus (strain Mayinga) and mutant virus infection. Samples were obtained from human hepatoma carcinoma cells (HUH-7)...
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Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Interferon Experiment IFNaHUH001 The purpose of this experiment was to evaluate the human host cellular response to treatment with and without interferon alpha/beta (IFNα/β) treatment. Sample time course data was obtained from human hepatoma...
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Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson MERS-CoV Experiment MCL001 The purpose of this experiment was to evaluate the human host response to wild-type Middle Eastern Respiratory Syndrome coronavirus (MERS-CoV), and mutants icMERS-CoV-RFP, icMERS-CoV-dNSP16, icMERS-CoV-d4B, and...
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Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson MERS-CoV Experiment MCL002 The purpose of this experiment was to evaluate the human host response to wild-type Middle Eastern Respiratory Syndrome coronavirus (MERS-CoV) and mutants icMERS-RFP, icMERS-DNSP16, and icMERS-d4B virus infection...
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Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Interferon Experiment IFNaIHH001 The purpose of this experiment was to evaluate the host interferon-stimulated cellular response to interferon alpha (IFNα) treatment. Sample data was obtained from human immortalized human hepatocyte cells (IHH...