Omics-LHV, West Nile Experiment WCD003 The purpose of this West Nile experiment was to obtain samples for omics analysis in mouse dendritic cell response to wild-type West Nile virus (WNV). Overall Design: Mouse dendritic cells (2 x 10^5) were treated with wild-type WNV and collected in parallel...

Omics-LHV, West Nile Experiment WCN004 The purpose of this West Nile experiment was to obtain samples for omics analysis in mouse cerebral cortex neurons in response to wild-type West Nile Virus (WNV; WNV-NY99 382) and mutant WNV-E218A (WNV-NY99 382) viral infection. Overall Design: Mouse cortical...

Omics-LHV, West Nile Experiment WGCN004 The purpose of this West Nile experiment was to obtain samples for omics analysis in primary mouse granule neuron cells infected with wild type West Nile virus (WNV-NY99 clone 382, WNVWT) and mutant virus (WNVE218A). Overall Design: Granule cell neurons from...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson PNNL DataHub NIAID Program Project: Modeling Host Responses to Understand Severe Human Virus Infections, Multi-Omic Viral Dataset Catalog Collection Background The National Institute of Allergy and Infectious Diseases (NIAID) "Modeling Host...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Omics-LHV Profiling of Host Response to MERS-CoV Virus Infection Background Middle East Respiratory Syndrome coronavirus ( MERS-CoV ), part of the Coronaviridae family, is classified as a Category C priority pathogen by the National Institute...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Omics-LHV Profiling of Host Response to Ebola Virus Infection Background Ebola virus ( EBOV ) is a high risk biological agent, belonging to the Flaviviridae family, and is classified as a Category A priority pathogen by the National Institute...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Omics-LHV Profiling of Host Response to Influenza A Virus Infection Background Influenza A virus ( IAV ) is a high risk biological agent belonging to the Orthomyxoviridae family is classified as a Category C priority pathogen by the National...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Omics-LHV Profiling of Host Response to West Nile Virus Infection Background West Nile virus ( WNV ) belongs to the mosquito-borne Flaviviridae family and is classified as a Category A priority pathogen by the National Institute of Allergy and...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Omics-LHV Profiling of Host Interferon-Stimulated Response to Virus Infection Background The human host Interferon ( IFN ) alpha, beta, and gamma participate in the body's natural immune response to lethal virus infection and disease. The...

Systems Virology Lethal Human Virus, SARS-CoV Experiment SCL005 New uploads pending The purpose of this experiment was to evaluate the human host response to wild type virus icSARS-CoV Urbani and mutant virus icSARS deltaORF6 (DORF6) infection for subsequent transcriptional and proteomic analysis in...

Systems Virology Lethal Human Virus, SARS-CoV Experiment SCL006 New uploads pending The purpose of this SARS experiment was to obtain samples for transcriptome and proteome analysis in human lung 2B4 cells (clonal derivative of Calu-3 cells) infected with wild type icSARS CoV Urbani and icSARS Bat...

Systems Virology Lethal Human Virus, SARS-CoV Experiment SCL008 New uploads pending The purpose of this SARS experiment was to obtain samples for transcriptome and proteome analysis in human lung 2B4 cells (clonal derivative of Calu-3 cells) infected with either icSARS CoV, icSARS-deltaNSP16 or...

Systems Virology Lethal Human Virus, SARS-CoV Experiment SCL009 New uploads pending The purpose of this SARS experiment was to obtain samples for metabolome and lipidome analysis comparing wild type virus (icSARS) infected Human lung tissue 2B4 (Calu-3 clonal derivative) cells to mock infected cells...

Systems Virology Lethal Human Virus, SARS-CoV Experiment SM003 New uploads pending The purpose of this SARS experiment was to obtain samples for transcriptome and proteome analysis in C57BlL/6 mice lung infected with dicSARS CoV, SARS MA15 wild type and SARS BatSRBD mutant virus. Overall Design...

Systems Virology Lethal Human Virus, SARS-CoV Experiment SM012 New uploads pending The purpose of this SARS experiment was to obtain samples for transcriptome and proteome analysis in C57Bl/6 mice infected with SARS MA15 or SARS deltaORF6 mutant viruses. Overall Design: Twenty-week-old C57BL/6 mice...