Agriculture is the largest source of greenhouse gases (GHG) production. Conversion of nitrogen fertilizers into more reduced forms by microbes through a process known as biological nitrification drives GHG production, enhances proliferation of toxic algal blooms, and increases cost of crop...
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Metabolite exchange between plant roots and their associated rhizosphere microbiomes underpins plant growth promotion by microbes. Sorghum bicolor is a cereal crop that feeds animals and humans and is used for bioethanol production. Its root tips exude large amounts of a lipophilic benzoquinone...
A major challenge in biotechnology and biomanufacturing is the identification of a set of biomarkers for perturbations and metabolites of interest. Here, we develop a data-driven, transcriptome-wide approach to rank perturbation-inducible genes from time-series RNA sequencing data for the discovery...
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The Phenotypic Response of the Soil Microbiome to Environmental Perturbations Project (Soil Microbiome SFA) at Pacific Northwest National Laboratory is a Genomic Sciences Program Science Focus Area (SFA) Project operating under the Environmental Microbiome Science Research Area. The Soil Microbiome...
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Short Biography Caroline (Carrie) Harwood received her Ph.D. in microbiology from the University of Massachusetts and completed postdoctoral work at Yale University. She held academic appointments at Cornell University and the University of Iowa before moving to the University of Washington in 2005...
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PerCon SFA, Co-Investigator Vivian Lin earned her PhD in organic chemistry from the University of California, Berkeley with Professor Chris Chang, developing fluorescent probes for imaging redox active small molecules. Afterward, she traveled to Switzerland for a postdoctoral fellowship in the...
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Stanford Synchrotron Radiation Lightsource Experimental Station 14-3b is a bending magnet side station dedicated to X-Ray Imaging and Micro X-Ray Absorption Spectroscopy of biological, biomedical, materials, and geological samples. Station 14-3b is equipped with specialized instrumentation for XRF...
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The Physical Electronics Instruments (PHI) Quantum 2000 X-Ray Photoelectron Spectrometer (XPS) is a unique Micro-Focused Scanning X-Ray system that uses a focused monochromatic aluminum K X-ray beam that can be varied in size from as small as 10 μm in diameter to approximately 200 μm. The beam can...
Systems Virology Lethal Human Virus, SARS-CoV Experiment SM003 New uploads pending The purpose of this SARS experiment was to obtain samples for transcriptome and proteome analysis in C57BlL/6 mice lung infected with dicSARS CoV, SARS MA15 wild type and SARS BatSRBD mutant virus. Overall Design...
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Systems Virology Lethal Human Virus, SARS-CoV Experiment SM012 New uploads pending The purpose of this SARS experiment was to obtain samples for transcriptome and proteome analysis in C57Bl/6 mice infected with SARS MA15 or SARS deltaORF6 mutant viruses. Overall Design: Twenty-week-old C57BL/6 mice...
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Systems Virology Lethal Human Virus, SARS-CoV Experiment SCL005 New uploads pending The purpose of this experiment was to evaluate the human host response to wild type virus icSARS-CoV Urbani and mutant virus icSARS deltaORF6 (DORF6) infection for subsequent transcriptional and proteomic analysis in...
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Systems Virology Lethal Human Virus, SARS-CoV Experiment SCL006 New uploads pending The purpose of this SARS experiment was to obtain samples for transcriptome and proteome analysis in human lung 2B4 cells (clonal derivative of Calu-3 cells) infected with wild type icSARS CoV Urbani and icSARS Bat...
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Systems Virology Lethal Human Virus, SARS-CoV Experiment SHAE003 New uploads pending The purpose of this SARS experiment was to obtain samples for transcriptome analysis in Human Airway Epithelial (HAE) cells infected with SARS-CoV, SARS deltaORF6, SARS BatSRBD mutants in a longitudinal study...