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Metabolite exchange between plant roots and their associated rhizosphere microbiomes underpins plant growth promotion by microbes. Sorghum bicolor is a cereal crop that feeds animals and humans and is used for bioethanol production. Its root tips exude large amounts of a lipophilic benzoquinone...

A major challenge in biotechnology and biomanufacturing is the identification of a set of biomarkers for perturbations and metabolites of interest. Here, we develop a data-driven, transcriptome-wide approach to rank perturbation-inducible genes from time-series RNA sequencing data for the discovery...

https://www.nih.gov/about-nih/what-we-do/mission-goals NIH’s mission is to seek fundamental knowledge about the nature and behavior of living systems and the application of that knowledge to enhance health, lengthen life, and reduce illness and disability. The goals of the agency are: to foster...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Omics-LHV Profiling of Host Response to Influenza A Virus Infection Background Influenza A virus ( IAV ) is a high risk biological agent belonging to the Orthomyxoviridae family is classified as a Category C priority pathogen by the National...

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Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson PNNL DataHub NIAID Program Project: Modeling Host Responses to Understand Severe Human Virus Infections, Multi-Omic Viral Dataset Catalog Collection Background The National Institute of Allergy and Infectious Diseases (NIAID) "Modeling Host...

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Dr. Katrina Waters is the division director for Biological Sciences at the Pacific Northwest National Laboratory. Waters has a Ph.D. in biochemistry and more than 15 years of experience in microarray and proteomics data analysis. Her research interests are focused on the integration of genomics...

Short Biography Caroline (Carrie) Harwood received her Ph.D. in microbiology from the University of Massachusetts and completed postdoctoral work at Yale University. She held academic appointments at Cornell University and the University of Iowa before moving to the University of Washington in 2005...

PerCon SFA, Co-Investigator Vivian Lin earned her PhD in organic chemistry from the University of California, Berkeley with Professor Chris Chang, developing fluorescent probes for imaging redox active small molecules. Afterward, she traveled to Switzerland for a postdoctoral fellowship in the...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Influenza A Virus Experiment ICL102 The purpose of this experiment was to evaluate the human host cellular response to Influenza A virus (subtype H7N9) , wild-type strain Influenza A/Anhui/1/2013 (AH1-WT), and mutant viruses NS1-L103F/I106M...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Influenza A Virus Experiment ICL103 The purpose of this experiment was to evaluate the human host response to Influenza A virus (subtype H5N1) and mutant viruses. Sample data was obtained for human lung adenocarcinoma cell line (Calu-3)...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Influenza A Virus Experiment IM102 The purpose of this experiment was to evaluate the mouse host response to Influenza A virus (subtype H7N9) wild-type strain Influenza A/Anhui/1/2013 (AH1-WT) virus and mutants NS1-103F/106M (AH1-F/M) and...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Influenza A Virus Experiment IM103 The purpose of this experiment was to evaluate the host response to Influenza A virus (subtype H5N1) wild-type strain Influenza A/Vietnam/1203/2004 (VN1203) virus, mutant VN1203-NS1trunc124, and mock...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Influenza A Virus Experiment ICL104 The purpose of this experiment was to evaluate the host response to pandemic Influenza A virus (subtype H1N1) , natural isolate Influenza A/California/04/2009 virus. Sample data was obtained from human lung...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Influenza A Virus Experiment IM101 The purpose of this experiment was to evaluate the host mouse response to Influenza A virus (subtype H5N1) wild-type strain Influenza A/Vietnam/1203/2004, Influenza A/Vietnam/1203/2004 mutant strains PB2-627E...

Systems Virology Lethal Human Virus, SARS-CoV Experiment SCL006 New uploads pending The purpose of this SARS experiment was to obtain samples for transcriptome and proteome analysis in human lung 2B4 cells (clonal derivative of Calu-3 cells) infected with wild type icSARS CoV Urbani and icSARS Bat...