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Showing 121 - 135 of 274
Publication
A Network Integration Approach to Predict Conserved Regulators Related to Pathogenicity of Influenza and SARS-CoV Respiratory Viruses
Respiratory infections stemming from influenza viruses and the Severe Acute Respiratory Syndrome corona virus (SARS-CoV) represent a serious public health threat as emerging pandemics. Despite efforts to identify the critical interactions of these viruses with host machinery, the key regulatory...
Biology
Human Health
Dataset
Systems Virology Lethal Human Virus, SARS-CoV Experiment SHAE004

Systems Virology Lethal Human Virus, SARS-CoV Experiment SHAE004 New uploads pending The purpose of this SARS experiment was to obtain samples for transcriptome analysis in Human Airway Epithelial (HAE) cells infected with SARS-CoV, SARS deltaORF6, SARS BatSRBD mutants in a longitudinal study...

Biology
Human Health
Publication
Validation of the Community Land Model Version 5 over the Contiguous United States (CONUS) using in-situ and remote sensing datasets
The Community Land Model (CLM) is an effective tool to simulate the biophysical and biogeochemical processes and their interactions with the atmosphere. Although CLM Version 5 (CLM5) constitutes various updates in these processes, its performance in simulating energy, water and carbon cycles over...
Atmospheric Science
Dataset
Omics-Lethal Human Viruses, MERS-CoV Experiment MCL003

MERS-CoV Experiment MCL003 The purpose of this experiment was to evaluate the human host response to wild-type icMERS-CoV virus infection and mockulum. Sample data was obtained from human lung adenocarcinoma cells (Calu-3) for proteome, metabolome, and lipidome expression analysis. Resulting...

Biology
Human Health
Integrative Omics
Project
NIAID Modeling Host Responses to Understand Severe Human Virus Infections Research Program Processed Data

Reusable Digital Data Lifecycle Downloads for Modeling Host Responses to Understand Severe Human Virus Infections The National Institute of Allergy and Infectious Diseases (NIAID) "Modeling Host Responses to Understand Severe Human Virus Infections" (U19AI106772) program project was a highly...

Biology
Human Health
Integrative Omics

  1. Datasets

    49
Dataset
Omics-Lethal Human Viruses, Influenza A Experiment IM104

Influenza A Experiment IM104 Processed Omics Data Unavailable This Influenza experiment evaluated mouse lung expression after etoposide treatment and infection with a pandemic H1N1 influenza strain. Related Experimental Data BioProject: PRJNA382278 GEO: GSE97555 (mRNA transcriptome response)...

Biology
Human Health
Integrative Omics
Publication
MERS-CoV and H5N1 influenza virus antagonize antigen presentation by altering the epigenetic landscape
Both highly pathogenic avian influenza virus and Middle East respiratory syndrome coronavirus (MERS-CoV) infections are characterized by severe disease and high mortality. The continued threat of their emergence from zoonotic populations underscores an important need to understand the dynamics of...
Biology
Human Health
Publication
Multi-platform ’Omics Analysis of Human Ebola Virus Disease Pathogenesis
The pathogenesis of human Ebola virus disease (EVD) is complex. EVD is characterized by high levels of virus replication and dissemination, dysregulated immune responses, extensive virus- and host-mediated tissue damage, and disordered coagulation. To clarify how host responses contribute to EVD...
Biology
Human Health
Dataset
Omics-Lethal Human Viruses, Ebola Experiment EH001

Ebola Experiment EH001 The purpose of this experiment was to evaluate the human patient peripheral blood mononuclear cells (PBMC) response to Zaire Ebola Makona virus infection during the 2013-2016 epidemic in West Africa. Sample were obtained from whole blood collections from patients and...

Biology
Human Health
Integrative Omics
Dataset
Datasets used for Validation of the Community Land Model Version 5 over the Contiguous United States (CONUS) using in-situ and remote sensing datasets
The dataset consists of model outputs (CLM45BGC, CLM5BGC, and CLM5SP) There are three CLM simulations associated with Cheng et al. 2020, namely CLM4.5 in biogeochemistry mode (CLM45BGC), CLM5 in biogeochemistry mode (CLM5BGC), and CLM5in satellite phenology mode (CLM5SP). The monthly, daily and...
Atmospheric Science
Dataset
FACETS Dynamical Downscaling Simulations over North America by the CAM-MPAS Variable-Resolution Model

Comprehensive assessment of climate datasets created by statistical or dynamical models is important for effectively communicating model projection and associated uncertainty to stakeholders and decision-makers. The Department of Energy FACETS project aims to foster such communication through...

Atmospheric Science
Dataset
WA-IsoC_MSC1.1.0 (Amplicon 16S rRNA, WA)

The soil microbiome is central to the cycling of carbon and other nutrients and to the promotion of plant growth. Despite its importance, analysis of the soil microbiome is difficult due to its sheer complexity, with thousands of interacting species. Here, we reduced this complexity by developing...

Biology
Earth System Science
Publication
Draft Genome of Fusarium sp. strain DS 682, a novel Fungal isolate from the Grass Rhizosphere
The novel fungal strain, Fusarium sp. DS 682, was isolated from the rhizosphere of the perennial grass, Bouteloua gracilis, at the Konza Prairie Biological Station in Kansas. This fungal strain is common across North American grasslands and is resilient to environmental fluctuations. The draft...
Earth System Science
Biology
Project
PREMIS-TAI: Beaver Creek Soil Incubation
Coastal landscapes are increasingly exposed to seawater due to sea level rise and extreme weather events. The biogeochemical responses of these vulnerable ecosystems are poorly understood, limiting our ability to predict how their role in global biogeochemical cycles will shift under future...
Coastal Science

  1. Datasets

    1
Dataset
KS4A-IsoG.1.0_FspDS682 (Fungal Monoisolate Genome, KS)
The novel fungal strain, Fusarium sp. DS 682, was isolated from the rhizosphere of the perennial grass, Bouteloua gracilis, at the Konza Prairie Biological Station in Kansas. This fungal strain is common across North American grasslands and is resilient to environmental fluctuations. The draft...
Biology
Earth System Science