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Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Interferon Experiment IFNMVE001 The purpose of this experiment was to evaluate the human host interferon-stimulated cellular response to interferon alpha/beta (IFNαβ) or gamma (INFγ) treatment. Sample data was obtained from primary lung...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Interferon Experiment IFNFB001 The purpose of this experiment was to evaluate the human host cellular response to interferon alpha/beta (IFNα/β) or interferon gamma (IFNγ) treatment. Sample data was obtained from primary human lung fibroblast...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Interferon Experiment IFNaIHH001 The purpose of this experiment was to evaluate the host interferon-stimulated cellular response to interferon alpha (IFNα) treatment. Sample data was obtained from human immortalized human hepatocyte cells (IHH...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Interferon Experiment IFNaCL001 The purpose of this experiment was to evaluate the host interferon-stimulated cellular response to interferon alpha (IFNα) treatment. Sample data was obtained from human lung adenocarcinoma cells (Calu-3)...

This dataset contains time series data collected from devices and sensors in the PNNL Systems Engineering Building collected using the VOLTTRON platform. The data includes readings from HVAC, power, and lighting systems and was collected between March and July of 2018. This work was funded by the...
Please cite as : Zegeye E., C.J. Brislawn, Y. Farris, S.J. Fansler, K.S. Hofmockel, J.K. Jansson, and A.T. Wright, et al. 2019. WA-IsoC_NAG.1.0 (Amplicon 16S/ITS, WA). [Data Set] PNNL DataHub. https://dx.doi.org/10.25584/data.2019-02.700/1506698 Investigation of the successional dynamics of a soil...
Dataset

The data accompanies the manuscript that evaluates salinity-associated shifts in organic C thermodynamics, biochemical transformations, and heteroatom content in a first-order coastal watershed in the Olympic Peninsula of Washington state, USA. The files contain raw data including soil chemical...

This study investigates how circadian clock regulation impacts carbon partitioning between storage, growth, and product synthesis in Synechococcus elongatus PCC 7942 in providing insights for potential strategies for enhanced bioproduction. In our analysis we explore circadian regulatory rewiring of...

The ability of high-density lipoprotein (HDL) to promote cellular cholesterol efflux is a more robust predictor of cardiovascular disease protection than HDL-cholesterol levels in plasma. Previously, we found that lipidated HDL containing both apolipoprotein A-I (APOA1) and A-II (APOA2) promotes...

Coronaviruses (CoV) emerge suddenly from animal reservoirs to cause novel diseases in new hosts. Discovered in 2012, the Middle East respiratory syndrome coronavirus (MERS-CoV) is endemic in camels in the Middle East and is continually causing local outbreaks and epidemics. While all three newly...

Climate change is expected to increase the frequency of hotter and more intense droughts accompanied by aberrant precipitation events. Such extreme environmental shifts can trigger a complex cascade of microbial physiological responses that can impact the microbial community structure and functions...

Please cite as: Graham E.B., and K.S. Hofmockel. 2021. "Ecological stoichiometry as a foundation for omics-enabled biogeochemical models of soil organic matter decomposition." Biogeochemistry 157. doi:10.1007/s10533-021-00851-2 Coupled biogeochemical cycles drive ecosystem ecology by influencing...

Metagenomics is unearthing the previously hidden world of soil viruses. Many soil viral sequences in metagenomes contain putative auxiliary metabolic genes (AMGs) that are not associated with viral replication. Here, we establish that AMGs on soil viruses actually produce functional, active proteins...

Soil viruses are highly abundant and have important roles in the regulation of host dynamics and soil ecology. Climate change is resulting in unprecedented changes to soil ecosystems and the life forms that reside there, including viruses. In this Review, we explore our current understanding of soil...

Abstract Microbial response to changing environmental factors influences the fate of soil organic carbon, and drought has been shown to affect microbial metabolism and respiration. We hypothesized that the access of microbes to different carbon pools in response to dry–rewet events occurs...