Soil fungi facilitate the translocation of inorganic nutrients from soil minerals to other microorganisms and plants. This ability is particularly advantageous in impoverished soils, because fungal mycelial networks can bridge otherwise spatially disconnected and inaccessible nutrient hotspots...
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"Deconstructing the Soil Microbiome into Reduced-Complexity Functional Modules" The soil microbiome represents one of the most complex microbial communities on the planet, encompassing thousands of taxa and metabolic pathways, rendering holistic analyses computationally intensive and difficult. Here...
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"Visualizing the Hidden Half: Plant-Microbe Interactions in the Rhizosphere" Plant roots and the associated rhizosphere constitute a dynamic environment that fosters numerous intra- and interkingdom interactions, including metabolite exchange between plants and soil mediated by root exudates and the...
Elmore JR, Dexter GN, Baldino H, Huenemann JD, Francis R, Peabody GL 5th, Martinez-Baird J, Riley LA, Simmons T, Coleman-Derr D, Guss AM, Egbert RG. High-throughput genetic engineering of nonmodel and undomesticated bacteria via iterative site-specific genome integration. Sci Adv. 2023 Mar 10;9(10)...
Metabolite exchange between plant roots and their associated rhizosphere microbiomes underpins plant growth promotion by microbes. Sorghum bicolor is a cereal crop that feeds animals and humans and is used for bioethanol production. Its root tips exude large amounts of a lipophilic benzoquinone...
Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Interferon Experiment IFNaHUH001 The purpose of this experiment was to evaluate the human host cellular response to treatment with and without interferon alpha/beta (IFNα/β) treatment. Sample time course data was obtained from human hepatoma...
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Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson MERS-CoV Experiment MCL001 The purpose of this experiment was to evaluate the human host response to wild-type Middle Eastern Respiratory Syndrome coronavirus (MERS-CoV), and mutants icMERS-CoV-RFP, icMERS-CoV-dNSP16, icMERS-CoV-d4B, and...
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Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Interferon Experiment IFNFB001 The purpose of this experiment was to evaluate the human host cellular response to interferon alpha/beta (IFNα/β) or interferon gamma (IFNγ) treatment. Sample data was obtained from primary human lung fibroblast...
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Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Interferon Experiment IFNMVE001 The purpose of this experiment was to evaluate the human host interferon-stimulated cellular response to interferon alpha/beta (IFNαβ) or gamma (INFγ) treatment. Sample data was obtained from primary lung...
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Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Interferon Experiment IFNaCL001 The purpose of this experiment was to evaluate the host interferon-stimulated cellular response to interferon alpha (IFNα) treatment. Sample data was obtained from human lung adenocarcinoma cells (Calu-3)...
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Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson Interferon Experiment IFNaIHH001 The purpose of this experiment was to evaluate the host interferon-stimulated cellular response to interferon alpha (IFNα) treatment. Sample data was obtained from human immortalized human hepatocyte cells (IHH...
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Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson MERS-CoV Experiment MHAE001 The purpose of this experiment was to evaluate the human host response to wild-type MERS-CoV (icMERS-CoV) virus infection. Sample data was obtained from primary human airway epithelial (HAE) cells for mRNA, miRNA...
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Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson MERS-CoV Experiment MHAE002 The purpose of this experiment was to evaluate the human host response to wild-type MERS-CoV (strain EMC-2012) virus infection. Sample data was obtained from primary human microvascular endothelial cells (HMVE) for...
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Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson MERS-CoV Experiment MHAE003 The purpose of this experiment was to evaluate the human host response to wild-type MERS-CoV (strain EMC-2012) infection. Sample data was obtained from primary human airway epithelial cells (HAE) for mRNA...
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Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson MERS-CoV Experiment MFB001 The purpose of this experiment was to evaluate the human host response to wild-type MERS-CoV (icMERS-CoV) virus infection. Sample data was obtained from primary human fibroblasts and processed for mRNA, miRNA...