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Human infections caused by viral pathogens trigger a complex gamut of host responses that limit disease, resolve infection, generate immunity, and contribute to severe disease or death. Here, we present experimental methods and multi-omics data capture approaches representing the global host...

https://www.nih.gov/about-nih/what-we-do/mission-goals NIH’s mission is to seek fundamental knowledge about the nature and behavior of living systems and the application of that knowledge to enhance health, lengthen life, and reduce illness and disability. The goals of the agency are: to foster...

Last updated on 2024-02-11T22:41:43+00:00 by LN Anderson PNNL DataHub NIAID Program Project: Modeling Host Responses to Understand Severe Human Virus Infections, Multi-Omic Viral Dataset Catalog Collection Background The National Institute of Allergy and Infectious Diseases (NIAID) "Modeling Host...

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The Phenotypic Response of the Soil Microbiome to Environmental Perturbations Project (Soil Microbiome SFA) at Pacific Northwest National Laboratory is a Genomic Sciences Program Science Focus Area (SFA) Project operating under the Environmental Microbiome Science Research Area. The Soil Microbiome...

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Dr. Katrina Waters is the division director for Biological Sciences at the Pacific Northwest National Laboratory. Waters has a Ph.D. in biochemistry and more than 15 years of experience in microarray and proteomics data analysis. Her research interests are focused on the integration of genomics...

PerCon SFA, Co-Investigator Vivian Lin earned her PhD in organic chemistry from the University of California, Berkeley with Professor Chris Chang, developing fluorescent probes for imaging redox active small molecules. Afterward, she traveled to Switzerland for a postdoctoral fellowship in the...

The Illumina MiSeq System Sequencer is a high-throughput DNA sequencer machine developed and manufactured by Illumina , and is designed for sequencing data acquisition using synthesis technology to provide an end-to-end solution (cluster generation, amplification, sequencing, and data analysis) in a...

The Illumina HiSeq X System Sequencer is a high-throughput DNA sequencer machine developed and manufactured by Illumina , and is designed for high throughput, production-scale sequencing laboratories. Built off the HiSeq 2500 System, harnessing the patterned flow cell technology originally developed...

The Illumina HiSeq 4000 System Sequencer is a high-throughput DNA sequencer machine developed and manufactured by Illumina , and is designed for high throughput, production-scale sequencing laboratories. Built off the HiSeq 2500 System and harnessing the patterned flow cell technology originally...

The Sequel II System Sequencer is a high-throughput DNA sequencer machine developed and manufactured by PacBio , and is designed for high throughput, production-scale sequencing laboratories. Originally released in 2015, the Sequel system provides Single Molecule, Real-Time (SMRT) sequencing core...

Please cite as : Bhattacharjee A., L.N. Anderson, T.D. Alfaro, A. Porras-Alfarro, A. Jumpponen, K.S. Hofmockel, and J.K. Jansson, et al. 2020. KS4A-IsoG.1.0_FspDS682 (Fungal Monoisolate Genome, KS). [Data Set] PNNL DataHub. https://doi.org/10.25584/KS4AIsoGFspDS682/1635527 The novel fungal strain...

Systems Virology Lethal Human Virus, SARS-CoV Experiment SCL008 New uploads pending The purpose of this SARS experiment was to obtain samples for transcriptome and proteome analysis in human lung 2B4 cells (clonal derivative of Calu-3 cells) infected with either icSARS CoV, icSARS-deltaNSP16 or...

Systems Virology Lethal Human Virus, SARS-CoV Experiment SCL009 New uploads pending The purpose of this SARS experiment was to obtain samples for metabolome and lipidome analysis comparing wild type virus (icSARS) infected Human lung tissue 2B4 (Calu-3 clonal derivative) cells to mock infected cells...

Systems Virology Lethal Human Virus, SARS-CoV Experiment SCL012 New uploads pending The purpose of this SARS experiment was to obtain samples for metabolome and lipidome analysis comparing wild type virus (icSARS) vs icSARS CoV deltaORF6 infected Human lung tissue 2B4 (Calu-3 clonal derivative)...

Systems Virology Lethal Human Virus, SARS-CoV Experiment SHAE004 New uploads pending The purpose of this SARS experiment was to obtain samples for transcriptome analysis in Human Airway Epithelial (HAE) cells infected with SARS-CoV, SARS deltaORF6, SARS BatSRBD mutants in a longitudinal study...