Comprised of 6,426 sample runs, The Environmental Determinants of Diabetes in the Young (TEDDY) proteomics validation study constitutes one of the largest targeted proteomics studies in the literature to date. Making quality control (QC) and donor sample data available to researchers aligns with...
HDF5 file containing 10,000 hydraulic transmissivity inputs and the corresponding hydraulic pressure field outputs for a two-dimensional saturated flow model of the Hanford Site. The inputs are generated by sampling a 1,000-dimensional Kosambi-Karhunen-Loève (KKL) model of the transmissivity field...
Inclusion levels of alternative splicing (AS) events of five different varieties (i.e. skipped exon (SE), retained intron (RI), alternative 5’ splice site (A5SS), alternative 3’ splice site (A3SS), and mutually exclusive exons (MXE)) were measured in human blood samples from two separate cohorts of...
Last updated on 2023-03-21T18:35:22+00:00 by LN Anderson SAGE-RTP RT-PCR Amplicon Sequencing Barcode Count Analysis Promoter expression data for five bacterial species associated with the Serine recombinase Assisted Genome Engineering (SAGE) research project. Raw Measurement Data NCBI BioProject...
Please cite as : McClure R.S., Y. Farris, R.E. Danczak, W.C. Nelson, H. Song, A. Kessler, and J. Lee, et al. 2022. Model Soil Consortium 2 (MSC-2) Bacterial Isolate Genomes. [Data Set] PNNL DataHub. https://doi.org/10.25584/PNNLDH/1986536 Model Soil Consortium 2 (MSC-2) Bacterial Isolate Genomes...
Rapid remodeling of the soil lipidome in response to a drying-rewetting event - Multi-Omics Data Package DOI Data package contents reported here are the first version and contain pre- and post-processed data acquisition and subsequent downstream analysis files using various data source instrument...
Please cite as : Anderson L.N., R. Wu, W.C. Nelson, J.E. McDermott, K.S. Hofmockel, and J.K. Jansson. 2021. KS-TmG.2.0 (Metagenome, KS). [Data Set] PNNL DataHub. https://doi.org/10.25584/KSTmG2/1770332 Soil samples were collected in triplicate in the fall of 2017 across the three grassland locations...
Please cite as : Anderson L.N., R. Wu, W.C. Nelson, J.E. McDermott, K.S. Hofmockel, and J.K. Jansson. 2021. WA-TmG.2.0 (Metagenome, WA). [Data Set] PNNL DataHub. https://doi.org/10.25584/WATmG2/1770324 Soil samples were collected in triplicate in the fall of 2017 across the three grassland...
Last updated on 2023-05-02T18:08:23+00:00 by LN Anderson Fungal Monoisolate Multi-Omics Data Package DOI "KS4A-Omics1.0_FspDS68" Molecular mechanisms underlying fungal mineral weathering and nutrient translocation in low nutrient environments remain poorly resolved, due to the lack of a platform for...
Omics Lethal Human Virus, SARS-CoV Experiment SM001 New uploads pending The purpose of this experiment was to evaluate the human host response to Severe Acute Respiratory Syndrome coronavirus (SARS-CoV) wild-type virus. Sample data was obtained for 20 week-old C57BL/6J mouse lung tissue infected...
"Moisture modulates soil reservoirs of active DNA and RNA viruses" Soil is known to harbor viruses, but the majority are uncharacterized and their responses to environmental changes are unknown. Here, we used a multi-omics approach (metagenomics, metatranscriptomics and metaproteomics) to detect...
A major challenge in biotechnology and biomanufacturing is the identification of a set of biomarkers for perturbations and metabolites of interest. Here, we develop a data-driven, transcriptome-wide approach to rank perturbation-inducible genes from time-series RNA sequencing data for the discovery...
The rhizosphere represents a dynamic and complex interface between plant hosts and the microbial community found in the surrounding soil. While it is recognized that manipulating the rhizosphere has the potential to improve plant fitness and health, engineering the rhizosphere microbiome through...
Agriculture is the largest source of greenhouse gases (GHG) production. Conversion of nitrogen fertilizers into more reduced forms by microbes through a process known as biological nitrification drives GHG production, enhances proliferation of toxic algal blooms, and increases cost of crop...
Metabolite exchange between plant roots and their associated rhizosphere microbiomes underpins plant growth promotion by microbes. Sorghum bicolor is a cereal crop that feeds animals and humans and is used for bioethanol production. Its root tips exude large amounts of a lipophilic benzoquinone...