Omics-LHV Systems Biology Modeling Host Response to Severe Acute Respiratory Syndrome (SARS) Infection The Systems Virology project was one of four systems biology contracts funded by the NIAID Systems Biology for Infectious Diseases Research Program from 2008-2013. The Systems Biology for...

Omics-Lethal Human Virus Computational Modeling & Omics Core Processed Data Collection The National Institute of Allergy and Infectious Diseases (NIAID) "Modeling Host Responses to Understand Severe Human Virus Infections" (U19AI106772) program project was a comprehensive and interactive systems...

Ebola Experiment EH001 Multi-platform omics analyses of peripheral blood mononuclear cells and plasma derived from human patients infected with Ebola ΔVP30 virus from Sierra Leone. Patients with fatal EVD succumbed to the infection before additional samples could be collected. In total, 29 samples...

Influenza A Experiment IM102 The purpose of this Influenza experiment was to obtain samples for mRNA, miRNA, proteomics, lipidomics, and metabolomics analysis in mouse lung infected with WT A/Anhui/1/2013 (H7N9; 'AH1'), AH - NS1-103F/106M, and AH1 - 691 (ferret adapted virus). Overall Design: Groups...

Influenza A Experiment ICL104 The purpose of this experiment was to evaluate the host response to Influenza A pandemic wild-type H1N1 (A/California/04/2009), natural isolate virus. Sample data was obtained for human Calu-3 cells infected with wild-type H1N1 virus (A/California/04/2009) for mRNA...

Influenza A Experiment ICL103 The purpose of this experiment was to evaluate the human host response to Influenza A wild-type (H5N1) virus and mutant viruses. Sample data was obtained for human lung adenocarcinoma cell line (Calu-3) infected with WT Influenza A/Vietnam/1203/2004 (H5N1, VN1203) and...

Influenza A Experiment ICL102 The purpose of this experiment was to evaluate the human host response to Influenza A wild-type (H7N9) virus and mutant viruses. Sample data was obtained for human lung adenocarcinoma cell line (Calu-3) infected with WT H7N9 (A/Anhui/1/2013; AH1) and NS1-L103F/I106M for...

Omics-LHV Profiling of Host Response to West Nile Virus Infection The OMICS-LHV project aimed to develop a comprehensive understanding of the host response to unique viruses that cause lethal infections in humans by using a systems biology approach, assembling a multidisciplinary team of researchers...

Omics-LHV Profiling of Host Response to Ebola Virus Infection The OMICS-LHV project aimed to develop a comprehensive understanding of the host response to unique viruses that cause lethal infections in humans by using a systems biology approach, assembling a multidisciplinary team of researchers...

Omics-LHV Profiling of Host Response to Middle Eastern Respiratory Syndrome Coronavirus Infection The OMICS-LHV project aimed to develop a comprehensive understanding of the host response to unique viruses that cause lethal infections in humans by using a systems biology approach, assembling a...

Omics-LHV Profiling of Host Interferon-Stimulated Response to Virus Infection The OMICS-LHV project aimed to develop a comprehensive understanding of the host response to unique viruses that cause lethal infections in humans by using a systems biology approach, assembling a multidisciplinary team of...