Showing 1 - 15 of 23

Omics-LHV, West Nile Experiment WCN004 The purpose of this West Nile experiment was to obtain samples for omics analysis in mouse cerebral cortex neurons in response to wild-type West Nile Virus (WNV; WNV-NY99 382) and mutant WNV-E218A (WNV-NY99 382) viral infection. Overall Design: Mouse cortical...

Omics-LHV, West Nile Experiment WGCN004 The purpose of this West Nile experiment was to obtain samples for omics analysis in primary mouse granule neuron cells infected with wild type West Nile virus (WNV-NY99 clone 382, WNVWT) and mutant virus (WNVE218A). Overall Design: Granule cell neurons from...

Omics-LHV, West Nile Experiment WCD003 The purpose of this West Nile experiment was to obtain samples for omics analysis in mouse dendritic cell response to wild-type West Nile virus (WNV). Overall Design: Mouse dendritic cells (2 x 10^5) were treated with wild-type WNV and collected in parallel...

Systems Virology Lethal Human Virus, SARS-CoV Experiment SHAE003 New uploads pending The purpose of this SARS experiment was to obtain samples for transcriptome analysis in Human Airway Epithelial (HAE) cells infected with SARS-CoV, SARS deltaORF6, SARS BatSRBD mutants in a longitudinal study...

Systems Virology Lethal Human Virus, SARS-CoV Experiment SHAE002 New uploads pending The purpose of this SARS experiment was to obtain samples for transcriptome analysis in Human Airway Epithelial (HAE) cells infected with SARS-CoV, SARS deltaORF6, SARS BatSRBD mutants in a longitudinal study...

Systems Virology Lethal Human Virus, SARS-CoV Experiment SCL012 New uploads pending The purpose of this SARS experiment was to obtain samples for metabolome and lipidome analysis comparing wild type virus (icSARS) vs icSARS CoV deltaORF6 infected Human lung tissue 2B4 (Calu-3 clonal derivative)...

Systems Virology Lethal Human Virus, SARS-CoV Experiment SCL009 New uploads pending The purpose of this SARS experiment was to obtain samples for metabolome and lipidome analysis comparing wild type virus (icSARS) infected Human lung tissue 2B4 (Calu-3 clonal derivative) cells to mock infected cells...

Systems Virology Lethal Human Virus, SARS-CoV Experiment SCL008 New uploads pending The purpose of this SARS experiment was to obtain samples for transcriptome and proteome analysis in human lung 2B4 cells (clonal derivative of Calu-3 cells) infected with either icSARS CoV, icSARS-deltaNSP16 or...

Systems Virology Lethal Human Virus, SARS-CoV Experiment SCL006 New uploads pending The purpose of this SARS experiment was to obtain samples for transcriptome and proteome analysis in human lung 2B4 cells (clonal derivative of Calu-3 cells) infected with wild type icSARS CoV Urbani and icSARS Bat...

Systems Virology Lethal Human Virus, SARS-CoV Experiment SCL005 New uploads pending The purpose of this experiment was to evaluate the human host response to wild type virus icSARS-CoV Urbani and mutant virus icSARS deltaORF6 (DORF6) infection for subsequent transcriptional and proteomic analysis in...

Systems Virology Lethal Human Virus, SARS-CoV Experiment SM012 New uploads pending The purpose of this SARS experiment was to obtain samples for transcriptome and proteome analysis in C57Bl/6 mice infected with SARS MA15 or SARS deltaORF6 mutant viruses. Overall Design: Twenty-week-old C57BL/6 mice...

Systems Virology Lethal Human Virus, SARS-CoV Experiment SM003 New uploads pending The purpose of this SARS experiment was to obtain samples for transcriptome and proteome analysis in C57BlL/6 mice lung infected with dicSARS CoV, SARS MA15 wild type and SARS BatSRBD mutant virus. Overall Design...

Systems Virology Lethal Human Virus, SARS-CoV Experiment SHAE004 New uploads pending The purpose of this SARS experiment was to obtain samples for transcriptome analysis in Human Airway Epithelial (HAE) cells infected with SARS-CoV, SARS deltaORF6, SARS BatSRBD mutants in a longitudinal study...

https://www.nih.gov/about-nih/what-we-do/mission-goals NIH’s mission is to seek fundamental knowledge about the nature and behavior of living systems and the application of that knowledge to enhance health, lengthen life, and reduce illness and disability. The goals of the agency are: to foster...
Despite high sequence similarity between pandemic and seasonal influenza viruses, there is extreme variation in host pathogenicity from one viral strain to the next. Identifying the underlying mechanisms of variability in pathogenicity is a critical task for understanding influenza virus infection...