This data package consists of data from human islets (n=6) treated with IFNγ + IL-1β for 24 h and subjected to top-down proteomics ( Table 1 ). Data contributors: Ashley N. Ives, Wei-Jun Qian & James M. Fulcher: Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA, 99354...

This data package consists of data from MIN6 cells treated with IL-1β + IFNγ + TNFα + palmitate for 24 h and submitted to proteomics analysis, and the same treatment for 8 h for metabolomics analysis (n=4) ( Table 1 ). This experimental design was set to study the possible roles of free fatty acids...

This data package consists of data from human islets (n=8) treated with IFNγ + IL-1β for 24 h and submitted to phosphoproteomics ( Table 1 ). Data contributor: Wei-Jun Qian: Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA, 99354, USA. Data repository: PXD011857...

This data package consists of data from human islets (n=5) treated with IFNγ + IL-1β with or without difluoromethylornithine (DFMO) and submitted to RNA-seq and proteomics analysis ( Table 1 ). DFMO is an inhibitor of ornithine decarboxylase (ODC), an enzyme of the polyamine pathway. Therefore, this...

This data package consists of data from parallel experiments compared to Pck001 but performed with EndoC-βH1 cells instead of human islets. Cells were treated with IFNγ + IL-1β for 48 h and submitted to RNA-seq (n=5), ATAC-seq (n=5), DNA methylation (n=5), and H3K27Ac ChIP-seq (n=4). In addition...

This data package consists of data from paired human islets treated with IFNγ + IL-1β for 48 h and submitted to RNA-seq (n=5), ATAC-seq (n=5), UMI-4C18 (n=2 or 3, depending on the viewpoint), and ChIP-seq for histone H3 lysine 27 acetylation (H3K27Ac) (n=4) ( Table 1 ). Islets across the study...

This data package consists of data from MIN6 cells (n=4) treated with IL-1β + IFNγ + TNFα for 24 h post RNAi targeting 85/88 kDa calcium-independent phospholipase A2 ( Pla2g6 ) and submitted to proteomics analysis ( Table 1 ). Pla2g6 is an enzyme that metabolizes phosphatidylcholine (PCs) into...

This data package contains processed LC-MS proteomics results and analysis scripts associated with the paper "Assessing Degenerate Peptide Resolution Methods using a Ground Truth Dataset". In this study, we designed an artificial microbial community to create a ground truth, simulated metaproteomic...

This repository contains data and code for the experiments run in the paper "Understanding Generative AI Content with Embedding Models" ( https://arxiv.org/abs/2408.10437 ). DataBase POC: Max Vargas (max.vargas@pnnl.gov) The data is separated by experiment: A. The `stack_exchange` dataset contains a...

Dataset Description The goal of the experiment was to demonstrate that the optimized multiplexed multi-PTM profiling workflow can comprehensively and quantitatively capture dynamic changes in protein abundance, cysteine oxidation, phosphorylation, and acetylation in cytokine-induced inflammatory...

This repository contains data for the experiments run in the paper "Understanding Generative AI Content with Embedding Models" ( https://arxiv.org/abs/2408.10437 ). DataBase POC: Max Vargas (max.vargas@pnnl.gov) The data is separated by experiment: A. The `stack_exchange` dataset contains a...

Dataset Description The purpose of this experiment was to evaluate the human host cellular response to wild type human coronavirus strain 229E (HCoV-229E) infection. Sample data was obtained for mock-infected and immortalized human lung fibroblasts (MRC-5) (MOI 5). Whole cell lysates were collected...

Created on 2024-10-16T17:27:40+00:00 by LN Anderson ; Last updated 2025-08-01T15:13:46+00:00. S. elongatus PCC 7942 LiP and TPP Structural Proteomics (JM-PB-DP3) The purpose of this experiment was to investigate structural alterations in proteins involved in central carbon metabolism and...

Currently pending public release.

Currently pending public release.